海外临床试验导航

胃癌

帮助用户按胃癌、胃食管结合部癌、HER2、CLDN18.2、PD-L1、MSI-H 等方向检索海外公开临床试验。

中文医学标准名
胃恶性肿瘤 / 胃食管结合部癌
英文医学标准名
Gastric Cancer / Gastroesophageal Junction Cancer
试验数据最后同步
2026-07-10

Synced trials

当前同步到的治疗类试验

以下记录来自公开临床试验数据库,已按招募状态、治疗目的、干预类型和癌症相关性做初步过滤。本站不判断患者是否符合入组条件,请以官方页面、医生和研究团队意见为准。

最后同步日期:2026-07-10 · 当前显示 533 条

招募状态和入组条件可能随时变化。请以官方页面、医院和研究机构信息为准,并带给主治医生或肿瘤科医生讨论。

状态
全部
试验阶段
全部
治疗类型
全部
国家/地区
全部
正在招募 Phase 1 药物
clinicaltrials.gov NCT06253871

A Phase 1/1b Study of IAM1363 in HER2 Cancers

适用疾病
HER2 Mutation-Related Tumors;HER2;HER2-positive Breast Cancer
干预
IAM1363
地点
United States,France,Ireland,Italy 等 4 个
申办方
Iambic Therapeutics, Inc
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06910657

IDOV-Immune for Advanced Solid Tumors

适用疾病
Colorectal Cancer;Pancreatic Cancer;Melanoma
干预
IDOV-Immune (oncolytic vaccinia virus)
地点
United States,Australia
申办方
ViroMissile, Inc.
即将招募 阶段未标明 手术/操作
clinicaltrials.gov NCT07237126

Single-port Robotic Radical Gastrectomy for Gastric Cancer

适用疾病
Gastric Cancer Patients Undergoing Gastrectomy
干预
Single-port Robotic Radical Gastrectomy for Gastric Cancer
地点
China
申办方
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
即将招募 阶段未标明 药物手术/操作
clinicaltrials.gov NCT06603974

The Efficacy and Safety of Benmelstobart for GC/EGC

适用疾病
Gastric Cancer
干预
surgery,Benmelstobart,tegafur,oxaliplatin
地点
未列出
申办方
Xijing Hospital
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04421820

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

适用疾病
Colorectal Cancer;Pancreatic Cancer;Gastric Cancers
干预
BOLD-100 +/- FOLFOX Chemotherapy (Arm VII),BOLD-100 in combination with FOLFOX Chemotherapy (Arms I-VI)
地点
United States,Canada,Germany,Ireland 等 3 个
申办方
Bold Therapeutics, Inc.
正在招募 Phase 2 药物手术/操作
clinicaltrials.gov NCT07655024

TAIC FOLFOX for Locally Advanced G/GEJA

适用疾病
Gastric Cancer (Diagnosis);Gastroesophageal Junction Adenocarcinoma
干预
TAIC,FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin)
地点
China
申办方
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
即将招募 Phase 4 药物
clinicaltrials.gov NCT07502027

A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following Heterogeneous Radiotherapy as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Gastric or Gastroesophageal Junction Adenocarcinoma

适用疾病
Gastric Cancer (Diagnosis);Gastric Cancer (GC);Gastroesophageal Junction Adenocarcinoma
干预
Iparomlimab and Tuvonralimab (QL1706)
地点
未列出
申办方
Huazhong University of Science and Technology
正在招募 Phase 2, Phase 3 药物
clinicaltrials.gov NCT07221149

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

适用疾病
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
干预
Pumitamig,Folfox,Capox,Nivolumab
地点
United States,Argentina,Australia,Brazil 等 17 个
申办方
Bristol-Myers Squibb
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT07341737

SL-28 for Advanced Solid Tumours

适用疾病
Head & Neck Cancer;Pancreas Carcinoma;Pancreas Cancer, Metastatic
干预
SL-28,SL-28,SL-28
地点
Australia
申办方
Second Life Therapeutics
正在招募 Phase 2, Phase 3 药物手术/操作
clinicaltrials.gov NCT06232434

An Open Prospective Randomized Clinical Study of the Effectiveness, Tolerability and Safety of a Single Intraperitoneal Use of the Drug "Prospidelong, Powder for the Preparation of a Gel for Topical Use, 1000 mg in Vials, Package No. 1" in Patients With Disseminated Gastric Cancer, Phase I-II

适用疾病
Gastric Cancer With Peritoneal Dissemination
干预
Prospidelong,chemotherapy
地点
Belarus
申办方
Research Institute for Physical Chemical Problems of the Belarusian State University
即将招募 Phase 1 药物
clinicaltrials.gov NCT07358884

First in Human Study of QLS5316 in Solid Tumors

适用疾病
Solid Tumors;Colorectal Cancer;Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
干预
QLS5316
地点
未列出
申办方
Qilu Pharmaceutical Co., Ltd.
正在招募 Phase 3 药物
clinicaltrials.gov NCT06901531

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

适用疾病
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer;Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer;Metastatic Gastric Adenocarcinoma or Cancer
干预
zolbetuximab,Pembrolizumab,Capecitabine,Oxaliplatin
地点
United States,Australia,Belgium,Brazil 等 18 个
申办方
Astellas Pharma Global Development, Inc.
正在招募 阶段未标明 放疗
clinicaltrials.gov NCT04368702

CONFIRM: Magnetic Resonance Guided Radiation Therapy

适用疾病
Gastric Cancer;Invasive Breast Cancer;in Situ Breast Cancer
干预
Viewray MRIdian® Linac
地点
United States
申办方
Brigham and Women's Hospital
即将招募 阶段未标明 药物手术/操作
clinicaltrials.gov NCT07452471

Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy

适用疾病
Gastric Cancer;Postoperative Pain
干预
Ultrasound-guided Transversus Abdominis Plane (TAP) Block,Ropivacaine-Poloxamer 407 Hydrogel (Welpass®)
地点
South Korea
申办方
Gyeong-Jo Byeon, MD, PhD
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

适用疾病
Metastatic Breast Cancer;Metastatic Gastric Adenocarcinoma;Gastroesophageal Junction Adenocarcinoma
干预
Zongertinib,Trastuzumab deruxtecan,Trastuzumab emtansine,Trastuzumab
地点
United States,Belgium,China,France 等 6 个
申办方
Boehringer Ingelheim
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06242470

A Study of MGC026 in Participants With Advanced Solid Tumors

适用疾病
Advanced Solid Tumor;Advanced Cancer;Metastatic Cancer
干预
MGC026 Dose Escalation,MGC026 Dose for Expansion
地点
United States,Australia,United Kingdom
申办方
MacroGenics
即将招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT07453394

QLS5132 Combination Therapy in Advanced Solid Tumors

适用疾病
Gastric Cancer (GC);Non-small Cell Lung Cancer (NSCLC);Endometrial Cancer
干预
QLS5132; Bevacizumab,QLS5132; Platinum; Bevacizumab,QLS5132; Olaparib; Bevacizumab,QLS5132; QL1706; QL2107
地点
未列出
申办方
Qilu Pharmaceutical Co., Ltd.
正在招募 Phase 2, Phase 3 生物制剂药物
clinicaltrials.gov NCT07392892

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

适用疾病
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma;Metastatic Gastric Cancer;Gastroesophageal Junction Cancer
干预
PF-08634404,Chemotherapy,Nivolumab
地点
United States,China,Israel,Japan 等 2 个
申办方
Pfizer
正在招募 Phase 1, Phase 2 联合产品药物
clinicaltrials.gov NCT03526835

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

适用疾病
Advanced/Metastatic Solid Tumors;Colorectal Cancer;Gastric Cancer
干预
MCLA-158,MCLA-158 + Pembrolizumab,MCLA-158 + FOLFIRI,MCLA-158 + FOLFOX
地点
United States,Belgium,France,Netherlands 等 2 个
申办方
Merus B.V.
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07593820

A Phase I Interventional Open-label, Non-randomized Dose-escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Anti-tumor Activity of Autologous p95HER2.CAR-TECH2Me T Cells in Patients With Selected Advanced Cancers.

适用疾病
Metastatic Gastric Cancer;Metastatic Breast Cancer;Endometrial Cancer Metastatic
干预
p95HER2.CAR-TECH2Me
地点
Spain
申办方
Vall d'Hebron Institute of Oncology
即将招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT07594548

Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

适用疾病
Clinical Stage II Esophageal Adenocarcinoma AJCC v8;Clinical Stage III Esophageal Adenocarcinoma AJCC v8;Clinical Stage III Gastric Cancer AJCC v8
干预
Biospecimen Collection,Computed Tomography,Futibatinib,Magnetic Resonance Imaging
地点
United States
申办方
Northwestern University
正在招募 EARLY / Phase 1 药物
clinicaltrials.gov NCT07595237

A IIT Study of 177Lu-DOTA-SNA040

适用疾病
Advanced Solid Tumors (Such as Gastric Cancer);Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction);Advanced Solid Tumors (Such as Pancreatic Cancer)
干预
177Lu-DOTA-SNA040
地点
China
申办方
SmartNuclide Biopharma
正在招募 Phase 2 药物
clinicaltrials.gov NCT06632262

A Phase 2 Clinical Study of ABSK061 and ABSK043

适用疾病
HER2-Gastric/Gastroesophageal Junction Cancer;Urothelial Carcinoma;Non-Small Cell Lung Cancer
干预
ABSK061 + ABSK043,ABSK061+ABSK043 in combination with CAPOX
地点
China
申办方
Abbisko Therapeutics Co, Ltd
正在招募 Phase 3 药物
clinicaltrials.gov NCT07518147

A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment

适用疾病
Gastric Cancer;Gastroesophageal Junction Adenocarcinoma
干预
BL-M05D1,Paclitaxel,Docetaxel,Irinotecan hydrochloride
地点
China
申办方
Sichuan Baili Pharmaceutical Co., Ltd.
正在招募 Phase 2 联合产品药物
clinicaltrials.gov NCT03259867

Combination of TATE and PD-1 Inhibitor in Liver Cancer

适用疾病
Hepatocellular Carcinoma;Gastric Cancer
干预
Nivolumab Injectable Product,Trans-arterial tirapazamine embolization
地点
United States
申办方
Teclison Ltd.
正在招募 Phase 1, Phase 2 生物制剂药物
clinicaltrials.gov NCT06469944

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

适用疾病
Gastroesophageal Junction;Gastroesophageal Adenocarcinoma;Esophageal Neoplasms
干预
Pembrolizumab,Sacituzumab Tirumotecan (sac-TMT),Capecitabine,Leucovorin
地点
United States,Brazil,Chile,China 等 8 个
申办方
Merck Sharp & Dohme LLC
正在招募 Phase 1 药物
clinicaltrials.gov NCT05872295

IKS014 in Advanced Solid Tumors That Express HER2

适用疾病
Breast Cancer;Gastric Cancer;Gastroesophageal-junction Cancer
干预
IKS014
地点
United States,Australia,New Zealand,Singapore
申办方
Iksuda Therapeutics Ltd.
正在招募 Phase 2, Phase 3 药物手术/操作
clinicaltrials.gov NCT07001748

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

适用疾病
Gastric Adenocarcinoma;Gastroesophageal Junction Adenocarcinoma;Peritoneal Carcinomatosis
干预
Standard of Care Chemotherapy,Biospecimen Collection,Computed Tomography,Diagnostic Laparoscopy
地点
United States
申办方
ECOG-ACRIN Cancer Research Group
即将招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT07583810

Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma

适用疾病
Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma;Gastric Mucosa-Associated Lymphoid Tissue Lymphoma;Marginal Zone Lymphoma
干预
Biopsy Procedure,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07179692

CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors

适用疾病
Lung Cancer;Gastric Cancer;Colon Cancer
干预
CEA-targeted CAR-T cells,CEA-targeted CAR-T cells,CEA-targeted CAR-T cells
地点
China
申办方
Chongqing Precision Biotech Co., Ltd
正在招募 Phase 1 药物
clinicaltrials.gov NCT04999761

AB122 Platform Study

适用疾病
Advanced or Metastatic Solid Tumor;Pancreatic Ductal Adenocarcinoma;Colorectal Cancer
干预
AB122,AB122,TAS-116,AB122
地点
Japan
申办方
Taiho Pharmaceutical Co., Ltd.
即将招募 阶段未标明 手术/操作
clinicaltrials.gov NCT07260461

The Efficacy and Safety of Laparoscopic Proximal Gastrectomy With LPG-tbROSF Versus LTG for Localized Proximal Gastric Cancer.

适用疾病
Stomach Neoplasms;Adenocarcinoma - Gastroesophageal Junction (GEJ);Gastroesophageal Junction Cancer
干预
Laparoscopic Proximal Gastrectomy with Tubular Stomach-Based Right-Opening Single Flap Valvuloplasty (LPG-tbROSF)
地点
未列出
申办方
First Affiliated Hospital of Wenzhou Medical University
正在招募 Phase 1 药物
clinicaltrials.gov NCT06131840

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

适用疾病
Colorectal Neoplasms;Carcinoma, Non-Small-Cell Lung;Stomach Neoplasms
干预
PF-08046050,bevacizumab,5-Fluorouracil (5-FU),Oxaliplatin
地点
United States,Canada,China,France 等 5 个
申办方
Seagen, a wholly owned subsidiary of Pfizer
正在招募 Phase 2 药物
clinicaltrials.gov NCT07133490

INTERACT Stomach-II

适用疾病
Peritoneal Metastases From Gastric Cancer
干预
intraperitoneal chemotherapy
地点
Netherlands
申办方
Erasmus Medical Center
正在招募 Phase 1 药物
clinicaltrials.gov NCT07646106

THE-0504 in Patients With Solid Tumors

适用疾病
Small Cell Lung Cancer (SCLC);Colorectal Carcinoma (CRC);Gastric Cancer (GC)
干预
THE-0504
地点
Italy
申办方
Thena Biotech S.r.l.
正在招募 Phase 1 药物
clinicaltrials.gov NCT05107674

A Study of NX-1607 in Adults With Advanced Malignancies

适用疾病
Ovarian Cancer, Epithelial;Gastric Cancer;GastroEsophageal Junction (GEJ) Cancer
干预
NX-1607,Paclitaxel
地点
United States,United Kingdom
申办方
Nurix Therapeutics, Inc.
正在招募 Phase 3 药物
clinicaltrials.gov NCT05482516

Evaluating Novel Therapies in ctDNA Positive GI Cancers

适用疾病
Colon Adenocarcinoma;Rectal Adenocarcinoma;Gastric Adenocarcinoma
干预
Atezolizumab,Bevacizumab
地点
United States
申办方
Georgetown University
正在招募 Phase 3 药物
clinicaltrials.gov NCT06177041

M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma.

适用疾病
Locally Advanced Unresectable or Metastatic Gastric Cancer;Locally Advanced Unresectable or Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
干预
M108 monoclonal antibody,Placebo,Oxaliplatin,Capecitabine
地点
China
申办方
FutureGen Biopharmaceutical (Beijing) Co., Ltd
正在招募 Phase 3 药物
clinicaltrials.gov NCT06925243

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

适用疾病
Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]);Neoadjuvant Therapy;Adjuvant Chemotherapy
干预
Neoadjuvant apatinib combined with sintilimab and perioperative SOX,Neoadjuvant sintilimab combined with perioperative SOX
地点
China
申办方
Zuoyi Jiao
正在招募 Phase 1 药物
clinicaltrials.gov NCT04389632

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

适用疾病
Carcinoma, Non-Small Cell Lung;Squamous Cell Carcinoma of Head and Neck;HER2 Negative Breast Neoplasms
干预
sigvotatug vedotin,pembrolizumab,cisplatin,carboplatin
地点
United States,France,South Korea,Spain 等 3 个
申办方
Seagen, a wholly owned subsidiary of Pfizer
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06414733

HER-2 B Cell Peptide Vaccine

适用疾病
Metastatic Breast Cancer;Metastatic Gastrointestinal Carcinoma;HER2-positive Breast Cancer
干预
Combination of MVF-HER-2 (597-626) and MVF-HER-2 (266-296) emulsified with ISA 720
地点
United States
申办方
Pravin T.P Kaumaya
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT06364410

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

适用疾病
Clinical Stage III Gastric Cancer AJCC v8;Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8;Clinical Stage IV Gastric Cancer AJCC v8
干预
Azenosertib,Biopsy Procedure,Biospecimen Collection,Computed Tomography
地点
United States
申办方
National Cancer Institute (NCI)
即将招募 Phase 3 手术/操作
clinicaltrials.gov NCT07331454

Robotic vs Laparoscopic Gastrectomy for cT4a Gastric Cancer

适用疾病
Gastric Cancer (GC)
干预
Robotic Gastrectomy,Laparoscopic Gastrectomy
地点
China
申办方
The First Affiliated Hospital with Nanjing Medical University
正在招募 Phase 1 药物
clinicaltrials.gov NCT05005403

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

适用疾病
Non-Small Cell Lung Cancer;Head and Neck Squamous Cell Carcinoma;Micro Satellite Stable Colorectal Cancer
干预
Azirkitug,Budigalimab,Bevacizumab,Telisotuzumab Adizutecan
地点
United States,Canada,Israel,Japan 等 2 个
申办方
AbbVie
正在招募 Phase 1 药物
clinicaltrials.gov NCT04900818

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

适用疾病
Solid Tumor;Advanced Cancer;Metastatic Cancer
干预
TJ033721 (givastomig),TJ033721 (givastomig) , nivolumab, chemotherapy,TJ033721 (givastomig), chemotherapy,TJ033721 (givastomig), durvalumab, chemotherapy
地点
United States,China
申办方
I-Mab Biopharma US Limited
正在招募 Phase 2 诊断检测手术/操作
clinicaltrials.gov NCT07282912

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

适用疾病
Foregut Adenocarcinoma;Esophageal Adenocarcinoma;Gastroesophageal Adenocarcinoma
干预
Sequential cytoreductive intervention,Signatera Genome ultra-sensitive ctDNA blood test
地点
United States
申办方
Yale University
正在招募 Phase 2 药物
clinicaltrials.gov NCT04891016

Toripalimab Plus FLOT in Locally Advanced Gastric Cancer

适用疾病
Chemotherapy;Immune Checkpoint Inhibitor;Locally Advanced Gastric Carcinoma
干预
FLOT combined with toripalimab
地点
China
申办方
Henan Cancer Hospital
即将招募 Phase 2 药物手术/操作
clinicaltrials.gov NCT07266025

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma:A Randomized, Non-comparative Phase 2 Study

适用疾病
Gastric Adenocarcinoma;Gastroesophageal Adenocarcinoma;Mismatch Repair Deficient or MSI-High Solid Tumors
干预
Adebrelimab,XELOX,SHR-8068,D2 radical gastrectomy
地点
未列出
申办方
Shanghai Zhongshan Hospital
正在招募 Phase 2 药物
clinicaltrials.gov NCT05332002

sFOLFOXIRI in Advanced Gastroesophageal Cancer, (SAGE)

适用疾病
Gastro-Intestinal Cancer
干预
Four week alternating FOLFOX and FOLFIRI (sFOLFOXIRI)
地点
United States
申办方
Rutgers, The State University of New Jersey
正在招募 EARLY / Phase 1 生物制剂
clinicaltrials.gov NCT06937567

CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors

适用疾病
Biliary Tract Cancer;Colorectal Carcinoma;Gastric Cancer, Metastatic
干预
CDH17 CAR-T,FAST LACO-Stim CDH17 CAR-T
地点
China
申办方
Zhejiang University
即将招募 阶段未标明 手术/操作
clinicaltrials.gov NCT06934824

Clinical Study of Double-Endoscopic Combined With Minimally Invasive Treatment for Early Gastric Cancer at Clinical Stage T1b

适用疾病
Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
干预
Sixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und
地点
未列出
申办方
Hebei Medical University
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06943521

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

适用疾病
Head and Neck Squamous Cell Carcinoma (HNSCC);Non-small Cell Lung Cancer (NSCLC);Esophageal Cancer
干预
MT-4561
地点
United States,Japan
申办方
Tanabe Pharma America, Inc.
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05482893

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

适用疾病
Gastric or Gastroesophageal Junction Adenocarcinoma;Pancreatic Ductal Adenocarcinoma;Biliary Tract Cancer (BTC)
干预
Spevatamig (PT886),Paclitaxel,Gemcitabine,Abraxane
地点
United States
申办方
Phanes Therapeutics
正在招募 Phase 3 药物
clinicaltrials.gov NCT05264896

Perioperative FLOT vs Adjuvant XELOX for CA Stomach

适用疾病
Cancer of Stomach, Adenocarcinoma
干预
5-FU, Leucovorin, Oxaliplatin, Docetaxel,XELOX
地点
Hong Kong
申办方
Chinese University of Hong Kong
即将招募 Phase 2 药物
clinicaltrials.gov NCT06706895

A Single-arm, Single-center Phase II Clinical Study on the Clinical Efficacy and Safety of Paclitaxel Polymeric Micelles for Injection Combined With Fruquintinib Capsules in the Second-line Treatment of Patients With Advanced Gastric Cancer

适用疾病
Advanced Gastric Cancer;Paclitaxel Polymeric Micelles for Injection;Fruquintinib Capsules
干预
Paclitaxel Polymeric Micelles for Injection combined with Fruquintinib Capsules
地点
未列出
申办方
Shanghai Zhongshan Hospital
即将招募 Phase 3 药物手术/操作
clinicaltrials.gov NCT07508956

Feasibility of Circulating Tumor DNA Based Minimal Residual Disease-Guided Adjuvant Therapy in Locally Advanced Gastric Cancer With Neoadjuvant Treatment

适用疾病
Gastric / Gastroesophageal Junction Adenocarcinoma
干预
Standard neoadjuvant therapy: Chemotherapy/Targeted Therapy/Immunotherapy,Radical gastrectomy,Standard adjuvant therapy: Chemotherapy/Targeted Therapy/Immunotherapy,ctDNA-MRD-guided adjuvant therapy
地点
China
申办方
Shanghai Zhongshan Hospital
正在招募 阶段未标明 手术/操作
clinicaltrials.gov NCT06731998

Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

适用疾病
Oncologic Surgery;Cancer;Cancer Surgery
干预
Local Anesthesia,Laparoscopic Transversus Abdominis Plane block
地点
United States
申办方
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05086692

A Beta-only IL-2 ImmunoTherapY Study

适用疾病
Advanced Solid Tumor;Unresectable Solid Tumor;Clear Cell Renal Cell Carcinoma
干预
MDNA11,Pembrolizumab (KEYTRUDA®)
地点
United States,Australia,Canada,Ireland 等 3 个
申办方
Medicenna Therapeutics, Inc.
正在招募 Phase 2 药物
clinicaltrials.gov NCT07556640

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis: a Prospective, Exploratory Study

适用疾病
Gastric Cancer Stage IV;Peritoneal Metastases From Gastric Cancer;Gastric or Esophagogastric Junction Adenocarcinoma
干预
LM-302, S-1, paclitaxel,LM-302, Cadonilimab, S-1, paclitaxel
地点
China
申办方
Ruijin Hospital
正在招募 Phase 3 药物
clinicaltrials.gov NCT07431281

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

适用疾病
Gastric Cancer;Gastroesophageal Junction Adenocarcinoma;Esophageal Cancer
干预
Sonesitatug vedotin,Rilvegostomig,Nivolumab,Capecitabine
地点
United States,Australia,Austria,Belgium 等 18 个
申办方
AstraZeneca
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05187338

Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors

适用疾病
Lung Cancer;Liver Cancer;Colorectal Cancer
干预
ipilimumab +pembrolizumab +durvalumab
地点
China
申办方
Second Affiliated Hospital of Guangzhou Medical University
正在招募 阶段未标明 行为干预手术/操作
clinicaltrials.gov NCT07441850

Digital Rehabilitation for Gastric Cancer Surgery After Neoadjuvant Therapy

适用疾病
Gastric Cancer
干预
perioperative multimodal rehabilitation program with telephone supervision,Usual Care,perioperative multimodal rehabilitation program with digital supervision
地点
China
申办方
Beijing Friendship Hospital
正在招募 Phase 2 药物
clinicaltrials.gov NCT07483554

IBI343 in Combination Therapy for Advanced Malignant Solid Tumors

适用疾病
CLDN18.2 Positive;Gastric/Gastroesophageal Junction Adenocarcinoma;Pancreatic Ductal Adenocarcinoma
干预
IBI343,Gemcitabine, Albumin-bound Paclitaxel
地点
China
申办方
Innovent Biologics (Suzhou) Co. Ltd.
正在招募 Phase 2 药物放疗
clinicaltrials.gov NCT07165847

Neoadjuvant Radiotherapy Plus Tegafur, Oxaliplatin and Iparomlimab and Tuvonralimab in Resectable Gastric and GE-junction Cancer : A Randomized, Two-arm, Prospective Trial (TRIUNITE-05)

适用疾病
Immunotherapy;Gastric Cancer (GC);Radiotherapy
干预
Iparomlimab and Tuvonralimab,Oxaliplatin,Tegafur,Radiotherapy
地点
China
申办方
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
即将招募 Phase 3 药物
clinicaltrials.gov NCT06093425

Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma

适用疾病
Gastric Cancer;Gastroesophageal-junction Cancer;Advanced Cancer
干预
Pembrolizumab and either Capcecitabine + Oxaliplatin or Oxaliplatin+Leucovorin + 5-fluorouracil,Pembrolizumab and either Capcecitabine + Oxaliplatin or Oxaliplatin+Leucovorin + 5-fluorouracil
地点
未列出
申办方
Suzhou Transcenta Therapeutics Co., Ltd.
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06710756

Lead-212 PSV359 Therapy for Patients With Solid Tumors

适用疾病
Pancreatic Ductal Adenocarcinoma;Gastric Cancer;Esophageal Cancer
干预
[203Pb]Pb-PSV359,[212Pb]Pb-PSV359
地点
United States
申办方
Perspective Therapeutics
正在招募 阶段未标明 手术/操作
clinicaltrials.gov NCT07142122

Safety Comparison of Total Laparoscopic Proximal Gastrectomy With or Without Preservation of the Celiac Branch of the Vagus Nerve for Early Upper Gastric Cancer: A Randomized Controlled Clinical Trial

适用疾病
Gastric Cancer
干预
Total laparoscopic proximal gastrectomy with preservation of both the hepatic and celiac branches of the vagus nerve, followed by double-tract reconstruction.,Total laparoscopic proximal gastrectomy with preservation of the hepatic branch of the vagus nerve but deliberate resection of the celiac branch, followed by double-tract reconstruction.
地点
China
申办方
Fujian Cancer Hospital
正在招募 阶段未标明 药物放疗
clinicaltrials.gov NCT06349044

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

适用疾病
Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric Adenocarcinoma;Hepatocellular Carcinoma;Biliary Tract Carcinoma
干预
Hypofractionated radiotherapy/SBRT(5-10Gy/fx,3-5 fx),Anti-PD-1 monoclonal antibody,Oxaliplatin and Capecitabine,Anti-VEGF 15mg/kg
地点
China
申办方
Zhejiang Cancer Hospital
正在招募 Phase 3 手术/操作
clinicaltrials.gov NCT06161207

3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer

适用疾病
Gastric Cancer;Surgery
干预
Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection
地点
China
申办方
Fujian Medical University
即将招募 Phase 2 药物
clinicaltrials.gov NCT06730581

Utidelone Capsule Monotherapy for Patients with Advanced Solid Tumors

适用疾病
Gastric Cancer Adenocarcinoma Metastatic;Ovarian Cancer;Bile Duct Cancer
干预
Utidelone Capsule 60mg/m2/d,Utidelone capsule 75mg/m2,Utidelone Capsule
地点
未列出
申办方
Beijing Biostar Pharmaceuticals Co., Ltd.
正在招募 Phase 2 药物
clinicaltrials.gov NCT06250036

Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer

适用疾病
Locally Advanced Gastric Adenocarcinoma;MSI-H/dMMR Gastric Cancer;MSI-H/dMMR Gastroesophageal-junction Cancer
干预
Single agent zimberelimab,Combination zimberelimab + domvanalimab
地点
United Kingdom
申办方
Royal Marsden NHS Foundation Trust
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06921928

Study for AZD4360 in Participants With Advanced Solid Tumours

适用疾病
Gastric Cancer;Gastroesophageal Junction Cancer;Biliary Tract Cancer
干预
AZD4360
地点
United States,China,Germany,Japan 等 1 个
申办方
AstraZeneca
正在招募 Phase 1 药物
clinicaltrials.gov NCT06769425

HS-10502 Combination Treatment in Patients With Advanced Solid Tumors

适用疾病
Recurrent Ovarian Cancer;HER2-negative;Advanced Breast Cancer
干预
HS-10502 + NHA,HS-10502 + HS-20093,HS-10502+ Apatinib,HS-10502 + HS-20089
地点
China
申办方
Jiangsu Hansoh Pharmaceutical Co., Ltd.
正在招募 Phase 2 药物
clinicaltrials.gov NCT07070466

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

适用疾病
Stomach Cancer Stage IV;Esophagus Cancer;Stomach Cancer
干预
Ivonescimab,5-Fluorouracil,Oxaliplatin,Leucovorin
地点
United States
申办方
Massachusetts General Hospital
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT07262619

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

适用疾病
Advanced Solid Tumors;MSI-H or dMMR Advanced Solid Tumors;MSI-H/dMMR Gastric Cancer
干预
EIK1005,pembrolizumab (KEYTRUDA® )
地点
United States,Australia,New Zealand
申办方
Eikon Therapeutics
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT04147078

Personalized DC Vaccine for Postoperative Cancer

适用疾病
Gastric Cancer;Hepatocellular Carcinoma;Non-Small-Cell Lung Cancer
干预
DC vaccine subcutaneous administration
地点
China
申办方
Sichuan University
正在招募 Phase 2 药物
clinicaltrials.gov NCT07554521

A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States

适用疾病
Advanced Unresectable Gastric Adenocarcinoma;Esophageal Squamous Cell Carcinoma;Advanced Gastroesophageal Adenocarcinoma
干预
Tislelizumab,Capecitabine,5-fluorouracil (5-FU),Oxaliplatin
地点
United States
申办方
BeOne Medicines
正在招募 Phase 1 药物
clinicaltrials.gov NCT05208762

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

适用疾病
Carcinoma, Non-Small-Cell Lung;Squamous Cell Carcinoma of the Head and Neck;Esophageal Squamous Cell Carcinoma
干预
PF-08046054,pembrolizumab
地点
United States,Belgium,Canada,China 等 7 个
申办方
Seagen, a wholly owned subsidiary of Pfizer
正在招募 Phase 1 药物
clinicaltrials.gov NCT06266299

A Study of KK2269 in Adult Participants With Solid Tumors

适用疾病
Advanced Solid Tumor;Metastatic Solid Tumor;Gastric Adenocarcinoma
干预
KK2269,Docetaxel
地点
United States,Japan
申办方
Kyowa Kirin Co., Ltd.
正在招募 阶段未标明 手术/操作
clinicaltrials.gov NCT06162767

Cancer of Esophagogastric Junction: Optimized Sweet Versus Ivor-Lewis

适用疾病
Esophagogastric Junction Carcinoma
干预
Esophagectomy by Ivor-Lewis Procedure,Esophagectomy by Optimized Sweet Procedure
地点
China
申办方
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
正在招募 Phase 3 药物放疗
clinicaltrials.gov NCT04821778

Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer

适用疾病
Esophagus Cancer;Esophagogastric Junction Cancer;Chemoradiation
干预
Radiotherapy,Platinum based chemotherapy,Paclitaxel based chemotherapy,Immunotherapy
地点
China
申办方
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
正在招募 Phase 2 药物放疗
clinicaltrials.gov NCT04656041

Folfox+Irinotecan+Chemort In Esophageal Cancer

适用疾病
Gastroesophageal Junction Adenocarcinoma;Esophagogastric Cancer
干预
FOLFOX/ nal-IRI,Paclitaxel,Carboplatin,Proton Radiation Therapy
地点
United States
申办方
Massachusetts General Hospital
正在招募 Phase 1 药物其他放疗
clinicaltrials.gov NCT04615013

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

适用疾病
Cervical Esophagus Adenocarcinoma;Clinical Stage II Esophageal Adenocarcinoma AJCC v8;Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
干预
Capecitabine,Carboplatin,Docetaxel,Fluorouracil
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 Phase 1 药物
clinicaltrials.gov NCT04511039

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

适用疾病
Advanced Malignant Solid Neoplasm;Clinical Stage III Gastroesophageal Junction Adenocarcinoma;Clinical Stage IV Gastroesophageal Junction Adenocarcinoma
干预
Trifluridine and Tipiracil Hydrochloride,Talazoparib Tosylate
地点
United States
申办方
Roswell Park Cancer Institute
第 1 页

Subtypes

建议拆分方向

gastric cancergastroesophageal junction cancer / GEJHER2-positiveCLDN18.2PD-L1MSI-H / dMMRadvanced gastric cancermetastatic gastric cancer

Keywords

英文搜索关键词

Keyword guide

这些关键词怎么理解

术语中文意思对找临床试验有什么用
胃癌 / Gastric cancer 发生在胃部的恶性肿瘤。海外记录中也常写 stomach cancer。 可以同时尝试 gastric cancer 和 stomach cancer。
胃食管结合部癌 / GEJ cancer 发生在胃和食管交界区域的癌症,部分试验会和胃癌一起招募。 搜索时可加入 gastroesophageal junction 或 GEJ。
HER2-positive 部分胃癌或 GEJ 癌存在 HER2 高表达或扩增。 可以找 HER2 靶向药、ADC、联合治疗相关试验。
CLDN18.2 Claudin 18.2 是胃癌中常见研究靶点之一。 可以找 CLDN18.2 antibody、CAR-T、ADC 等相关试验。
PD-L1 和免疫治疗相关的生物标志物,常用 CPS 表达。 免疫治疗试验可能要求 PD-L1 CPS 或按其分层。
MSI-H / dMMR 提示微卫星高度不稳定或错配修复异常。 可以找免疫治疗相关试验。

Recruitment status

常见招募状态

Recruiting正在招募,可能仍可申请参加。
Not yet recruiting尚未开始招募,可关注后续开放时间。
Active, not recruiting试验仍在进行,但通常不再招新患者。
Completed试验已经完成。
Terminated试验提前终止。
Unknown公开页面上的状态不明确或未及时更新。

Before contact

联系前准备资料

  • 病理诊断报告
  • 影像报告:CT / MRI / PET-CT
  • 既往治疗记录
  • 用药历史
  • 基因检测报告
  • 最近血液检查结果
  • 出院小结
  • 主治医生英文病情摘要,如果有
  • 护照和签证情况,如果考虑出国

Filters

搜索时重点关注

  • Recruiting / Not yet recruiting
  • Location
  • Age
  • Phase
  • Inclusion Criteria
  • Exclusion Criteria
  • Prior treatments
  • Biomarker / mutation requirements
  • ECOG performance status
  • 是否接受 international patients
  • 是否需要长期停留在试验所在地
  • 费用、保险、翻译、住宿和陪护安排

Ask your doctor

可以带去问医生的问题

  • 我的病理类型是否符合这个试验?
  • 我之前用过的药会不会影响入组?
  • 我是否需要做基因检测?
  • 这个试验是几期?主要目的是什么?
  • 参加试验会不会影响当前治疗?
  • 如果去国外参加,风险和成本大概有哪些?
  • 研究团队是否接受海外患者?
下一步提示

请将检索到的临床试验信息带给主治医生或肿瘤科医生讨论。本站不判断患者是否适合任何临床试验。