海外临床试验导航

淋巴瘤

帮助用户按 DLBCL、滤泡性淋巴瘤、霍奇金淋巴瘤、CAR-T、双抗等方向检索海外公开临床试验。

中文医学标准名
淋巴系统恶性肿瘤
英文医学标准名
Lymphoma
试验数据最后同步
2026-07-10

Synced trials

当前同步到的治疗类试验

以下记录来自公开临床试验数据库,已按招募状态、治疗目的、干预类型和癌症相关性做初步过滤。本站不判断患者是否符合入组条件,请以官方页面、医生和研究团队意见为准。

最后同步日期:2026-07-10 · 当前显示 1061 条

招募状态和入组条件可能随时变化。请以官方页面、医院和研究机构信息为准,并带给主治医生或肿瘤科医生讨论。

状态
全部
试验阶段
全部
治疗类型
全部
国家/地区
全部
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06649812

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

适用疾病
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements;Recurrent Diffuse Large B-Cell Lymphoma;Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
干预
Biopsy Procedure,Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06768905

IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

适用疾病
Non Hodgkin Lymphoma;Diffuse Large B Cell Lymphoma
干预
Iomab-B,CAR-T cell
地点
United States
申办方
University of Texas Southwestern Medical Center
即将招募 Phase 1 药物
clinicaltrials.gov NCT07638982

Axatilimab + CAR-T for High-Risk Lymphoma

适用疾病
Diffuse Large B Cell Lymphoma (DLBCL);Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma;High-grade B-cell Lymphoma (HGBCL)
干预
Axatilimab
地点
United States
申办方
Northside Hospital, Inc.
正在招募 Phase 2 器械药物基因治疗
clinicaltrials.gov NCT06500273

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

适用疾病
Large B-cell Lymphoma
干预
cemacabtagene ansegedleucel,Fludarabine,Cyclophosphamide,Foresight CLARITY™ IUO MRD test, powered by PhasED-Seq™
地点
United States,Australia,Canada,South Korea
申办方
Allogene Therapeutics
即将招募 Phase 2 药物
clinicaltrials.gov NCT06778902

AZA Combined with R-GemOx for Elderly DLBCL Patients

适用疾病
DLBCL - Diffuse Large B Cell Lymphoma
干预
azacytidine,R-GemOx
地点
China
申办方
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT06015880

Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

适用疾病
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;High Grade B-Cell Lymphoma;Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
干预
Biospecimen Collection,Computed Tomography,Lenalidomide,Mosunetuzumab
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 2 药物
clinicaltrials.gov NCT06158399

AZA Combined With RCHOP in P53-mutated DLBCL.

适用疾病
DLBCL - Diffuse Large B Cell Lymphoma;TP53
干预
Azacitidine in combination with R-CHOP
地点
China
申办方
The First Affiliated Hospital of Xiamen University
正在招募 Phase 2 药物手术/操作
clinicaltrials.gov NCT06682130

Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL

适用疾病
Diffuse Large B-cell Lymphoma(DLBCL)
干预
Group A:Patients with PR or ctDNA positivity after salvage treatment,Group B: Patients with CR and ctDNA negative after salvage treatment,Group C: Patients with SD/PD after posterior treatment
地点
China
申办方
The First Affiliated Hospital of Soochow University
即将招募 Phase 1 药物
clinicaltrials.gov NCT07424833

A Study of APG-3288 in Relapsed/Refractory Blood Cancers

适用疾病
Relapsed/Refractory Hematological Malignancies;Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia (CLL/SLL;Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL; Including Richter Transformation)
干预
APG-3288
地点
United States,China
申办方
Ascentage Pharma Group Inc.
即将招募 阶段未标明 生物制剂
clinicaltrials.gov NCT07412405

This Clinical Trial is a Single-arm, Non-randomized Pilot Trial to Determine the Safety of Administering Autologous Anti-C19 Cells (ARI-0001) and the Feasibility of Local CAR-T Cell Production in Patients Over 18 Years of Age With Relapsed/Refractory (R/R) CD19+ Hematologic Malignancies, Including R

适用疾病
Adult B-cell Acute Lymphoblastic Leukemia;Follicular Lymphoma (FL);Mantle Cell Lymphoma (MCL)
干预
ARI-0001 T cells with anti-CD19 chimeric antigen receptor (CAR-T)
地点
未列出
申办方
GUSTAVO SALGUERO
正在招募 Phase 2 药物
clinicaltrials.gov NCT04889716

CAR-T Followed by Bispecific Antibodies

适用疾病
Large B-cell Lymphoma;DLBCL - Diffuse Large B Cell Lymphoma
干预
mosunetuzumab,glofitamab,obinutuzumab
地点
United States
申办方
Abramson Cancer Center at Penn Medicine
正在招募 Phase 2 药物
clinicaltrials.gov NCT07451652

Low Dose Epcoritamab Plus GemOx in R/R DLBCL

适用疾病
Relapsed/Refractory Diffuse Large B Cell Lymphoma
干预
Epcoritamab,Gemcitabine (1000 mg/m2),Oxaliplatin
地点
Mexico
申办方
Hospital Universitario Dr. Jose E. Gonzalez
正在招募 Phase 2 生物制剂
clinicaltrials.gov NCT07288879

DALY II Japan/MB-CART2019.1 for DLBCL

适用疾病
DLBCL - Diffuse Large B Cell Lymphoma;CAR T Cell Therapy
干预
MB-CART2019.1
地点
Japan
申办方
Miltenyi Biomedicine GmbH
正在招募 Phase 1 基因治疗
clinicaltrials.gov NCT05836896

A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies

适用疾病
Neoplasms;Relapsed Diffuse Large B-cell Lymphoma (DLBCL);Refractory Diffuse Large B-cell Lymphoma (DLBCL)
干预
MDC-CAR-BCMA001 (BCMA directed CAR T-cells)
地点
Germany
申办方
Technische Universität Dresden
正在招募 Phase 2 药物
clinicaltrials.gov NCT06664411

Pola-ZR2P in Previously Untreated DLBCL

适用疾病
Diffuse Large B-cell Lymphoma
干预
Polatuzumab Vedotin, Zanubrutinib, Rituximab, Lenalidomide and Prednisone as Induction Therapy
地点
China
申办方
Navy General Hospital, Beijing
正在招募 Phase 1 药物
clinicaltrials.gov NCT05365659

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

适用疾病
B-cell Non-Hodgkin Lymphoma;Diffuse Large B Cell Lymphoma;Follicular Lymphoma
干预
IKS03
地点
United States,Australia,Canada,Italy 等 1 个
申办方
Iksuda Therapeutics Ltd.
即将招募 Phase 2 药物
clinicaltrials.gov NCT07654426

The CARDIOPROTECT Trial

适用疾病
Diffuse Large B-cell Lymphoma (DLBCL);Cardiotoxicity;Lymphoma
干预
Dexrazoxane,Dexrazoxane placebo,Doxorubicin,Liposomal Doxorubicin
地点
United States
申办方
Beth Israel Deaconess Medical Center
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT04792489

DALY II USA/ MB-CART2019.1 for DLBCL

适用疾病
Refractory Diffuse Large B Cell Lymphoma (DLBCL);Relapsed Diffuse Large B Cell Lymphoma;High Grade B-cell Lymphoma (HGBCL)
干预
zamtocabtagene autoleucel (MB-CART2019.1),Cyclophosphamide,Fludarabine,Bendamustine
地点
United States,Canada
申办方
Miltenyi Biomedicine GmbH
正在招募 Phase 3 生物制剂药物
clinicaltrials.gov NCT06717347

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

适用疾病
Diffuse Large B-Cell Lymphoma
干预
Zilovertamab vedotin,Rituximab,Cyclophosphamide,Doxorubicin
地点
United States,Argentina,Australia,Belgium 等 31 个
申办方
Merck Sharp & Dohme LLC
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06464861

Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma

适用疾病
Primary Mediastinal B-cell Lymphoma (PMBCL);Mantle Cell Lymphoma (MCL);Diffuse Large B Cell Lymphoma( DLBCL)
干预
CD19-CAR-NK/T
地点
China
申办方
Second Affiliated Hospital, School of Medicine, Zhejiang University
正在招募 Phase 2 药物
clinicaltrials.gov NCT06701357

CR-CHOP+X in Previously Untreated DEL

适用疾病
DLBCL
干预
CR-CHOP+PD1 inhibitor,CR-CHOP + Orelabrutinib,CR-CHOP + decitabine
地点
China
申办方
Ruijin Hospital
正在招募 Phase 1 药物
clinicaltrials.gov NCT05107674

A Study of NX-1607 in Adults With Advanced Malignancies

适用疾病
Ovarian Cancer, Epithelial;Gastric Cancer;GastroEsophageal Junction (GEJ) Cancer
干预
NX-1607,Paclitaxel
地点
United States,United Kingdom
申办方
Nurix Therapeutics, Inc.
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05826535

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

适用疾病
Relapsed Non-Hodgkin Lymphoma;Refractory Non-Hodgkin Lymphoma;Non-Hodgkin Lymphoma
干预
Rondecabtagene autoleucel (ronde-cel),Fludarabine,Cyclophosphamide
地点
United States,Australia
申办方
Lyell Immunopharma, Inc.
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06594640

R-CMOP in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma

适用疾病
Diffuse Large B-cell Lymphoma
干预
Mitoxantrone Hydrochloride Liposome,Rituximab (R),Cyclophosphamide (CTX),Vincristin
地点
China
申办方
Institute of Hematology & Blood Diseases Hospital, China
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT05757219

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

适用疾病
Diffuse Large B Cell Lymphoma
干预
Itacitinib,Chimeric antigen receptor (CAR) T-cell therapy
地点
United States
申办方
H. Lee Moffitt Cancer Center and Research Institute
即将招募 Phase 2 药物
clinicaltrials.gov NCT07326371

Glofitamab Combined With CAR-T Therapy in R/R DLBCL

适用疾病
DLBCL - Diffuse Large B Cell Lymphoma
干预
Glofitamab,Obinutuzumab,Axicabtagene Ciloleucel,Relmacabtagene autoleucel (relma-cel)
地点
未列出
申办方
Ruijin Hospital
正在招募 Phase 1 药物
clinicaltrials.gov NCT05131022

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

适用疾病
Chronic Lymphocytic Leukemia (CLL);Small Lymphocytic Lymphoma (SLL);Diffuse Large B Cell Lymphoma (DLBCL)
干预
NX-5948
地点
United States,France,Italy,Netherlands 等 4 个
申办方
Nurix Therapeutics, Inc.
正在招募 Phase 1 生物制剂药物放疗
clinicaltrials.gov NCT07478848

Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

适用疾病
Large B Cell Lymphoma;Non Hodgkin Lymphoma (NHL);Diffuse Large B Cell Lymphoma (DLBCL)
干预
Vancomycin 125mg,Radiation Therapy,CAR-T
地点
United States
申办方
Abramson Cancer Center at Penn Medicine
正在招募 Phase 1 药物
clinicaltrials.gov NCT05544019

Study of SGR-1505 in Mature B-Cell Neoplasms

适用疾病
Mature B-Cell Neoplasm;Non Hodgkin Lymphoma;DLBCL
干预
SGR-1505
地点
United States,France,Italy,Moldova 等 4 个
申办方
Schrödinger, Inc.
正在招募 Phase 2 药物
clinicaltrials.gov NCT06811272

Outpatient Epcoritamab as 2L in NTE R/R DLBCL

适用疾病
Relapsed Large B-cell Lymphoma;Refractory Large B-cell Lymphoma
干预
Epcoritamab
地点
United States
申办方
Massachusetts General Hospital
正在招募 Phase 1 药物
clinicaltrials.gov NCT05512390

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

适用疾病
Diffuse Large B-Cell Lymphoma;Chronic Lymphocytic Leukemia;Follicular Lymphoma
干预
ABBV-319
地点
United States,Australia,Canada,Israel 等 2 个
申办方
AbbVie
即将招募 Phase 2, Phase 3 药物
clinicaltrials.gov NCT06355401

Maintenance Hormonal Therapy and DLBCL

适用疾病
Diffuse Large B Cell Lymphoma
干预
Tamoxifen 20mg
地点
未列出
申办方
Sohag University
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06544265

SynKIR-310 for Relapsed/Refractory B-NHL

适用疾病
B Cell Lymphoma;NHL, Adult;Mantle Cell Lymphoma
干预
SynKIR-310
地点
United States
申办方
Verismo Therapeutics
正在招募 Phase 2 药物
clinicaltrials.gov NCT06086197

A-RGEMOX in the Treatment of Early Relapsed/Refractory DLBCL

适用疾病
Diffuse Large B-cell Lymphoma Recurrent;Diffuse Large B Cell Lymphoma Refractory
干预
Anlotinib hydrochloride, Rituximab, gemcitabine, oxaliplatin
地点
China
申办方
Zhejiang Cancer Hospital
正在招募 Phase 2 生物制剂
clinicaltrials.gov NCT06854159

Odronextamab for the Treatment of Relapsed and Refractory Diffuse Large B-cell Lymphoma Before and After Chimeric Antigen Receptor T-cell Therapy

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma;Refractory Diffuse Large B-Cell Lymphoma
干预
Chimeric Antigen Receptor T-Cell Therapy,Odronextamab
地点
United States
申办方
University of California, Davis
正在招募 阶段未标明 药物
clinicaltrials.gov NCT07006012

RGL-305+ Lymphoma + Exploratory Clinical Study

适用疾病
Lymphoma Patients With Complete Response (CR) or Partial Response (PR) After Standard Treatment Had a Positive Minimal Residual Lesion (MRD)
干预
RGL-305
地点
China
申办方
Fudan University
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT06890884

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

适用疾病
Lymphoma, Large B-Cell, Diffuse
干预
Zilovertamab vedotin,Rituximab,Cyclophosphamide,Doxorubicin
地点
United States,Belgium,Germany,Ireland 等 5 个
申办方
Merck Sharp & Dohme LLC
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT07365306

Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified;Recurrent Primary Mediastinal Large B-Cell Lymphoma
干预
Autologous Hematopoietic Stem Cell Transplantation,Biopsy Procedure,Biospecimen Collection,Bone Marrow Aspiration
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 1 药物
clinicaltrials.gov NCT07691606

A Study of ARC-02 in B-cell NHL

适用疾病
B-cell Non Hodgkin Lymphoma
干预
ARC-02,Rituximab
地点
United States,Australia,France,Italy 等 2 个
申办方
Taiho Oncology, Inc.
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04390737

Evaluate the Safety and Clinical Activity of HH2853

适用疾病
FL Lymphoma;Epithelioid Sarcoma;Peripheral T Cell Lymphoma
干预
HH2853 Tablets
地点
United States,China
申办方
Haihe Biopharma Co., Ltd.
正在招募 Phase 1 药物
clinicaltrials.gov NCT06026319

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

适用疾病
Non-hodgkin Lymphoma;Relapsed Non-Hodgkin Lymphoma;Refractory Non-Hodgkin Lymphoma
干预
CD79b-19 CAR T cells,Cyclophosphamide,Fludarabine
地点
United States
申办方
Marcela V. Maus, M.D.,Ph.D.
正在招募 Phase 2 药物
clinicaltrials.gov NCT06959732

Zanubrutinib Combined With G-CVP in Previously Untreated FL

适用疾病
Follicular Lymphoma ( FL)
干预
zanubrutinib, obinutuzumab,combined with CVP
地点
China
申办方
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
正在招募 Phase 2 药物
clinicaltrials.gov NCT06563596

Epco, Zanu, Ritux for R/R FL or MZL

适用疾病
Follicular Lymphoma;Lymphoma;Non-Hodgkin Lymphoma
干预
Zanubrutinib,Rituximab,Epcoritamab
地点
United States
申办方
Reid Merryman, MD
正在招募 Phase 1, Phase 2 生物制剂手术/操作
clinicaltrials.gov NCT07098364

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;Recurrent Grade 3b Follicular Lymphoma
干预
Vevoctadekin,Bone Marrow Aspiration,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
Fred Hutchinson Cancer Center
正在招募 Phase 1, Phase 2 基因治疗
clinicaltrials.gov NCT06533579

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

适用疾病
B-cell Acute Lymphoblastic Leukemia;Large B-cell Lymphoma;Chronic Lymphocytic Leukemia
干预
Dose Level 1, VNX-101,Dose Level 2, VNX-101,Dose Level 3, VNX-101,Dose Level 4, VNX-101
地点
United States
申办方
Vironexis Biotherapeutics Inc.
正在招募 Phase 2 生物制剂
clinicaltrials.gov NCT07128641

Odronextamab in Low Tumor Volume Advanced FL

适用疾病
Follicular Lymphoma;Lymphoma
干预
Odronextamab
地点
United States
申办方
Gottfried von Keudell, MD PhD
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT04186520

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

适用疾病
Non Hodgkin Lymphoma (NHL);Mantle Cell Lymphoma (MCL);Chronic Lymphocytic Leukemia (CLL)
干预
8/12-Day Production of Car-T Cells,8/12-Day Production of Cryopreserved Car-T Cells,12-Day Production of Car-T Cells
地点
United States
申办方
Medical College of Wisconsin
正在招募 Phase 3 药物
clinicaltrials.gov NCT01804686

A Long-term Extension Study of PCI-32765 (Ibrutinib)

适用疾病
Chronic Lymphocytic Leukemia;Small Lymphocytic Lymphoma;Mantle Cell Lymphoma
干预
Ibrutinib
地点
United States,Argentina,Australia,Belgium 等 26 个
申办方
Janssen Research & Development, LLC
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT06191887

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

适用疾病
B-Cell Non-Hodgkin Lymphoma;Recurrent Chronic Lymphocytic Leukemia;Recurrent Diffuse Large B-Cell Lymphoma
干预
Autologous BAFFR-targeting CAR T Cells,Bendamustine,Biopsy,Biospecimen Collection
地点
United States
申办方
Mayo Clinic
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT06209619

CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma

适用疾病
B-Cell Non-Hodgkin Lymphoma-Recurrent;Diffuse Large B-Cell Lymphoma-Recurrent;Follicular Lymphoma-Recurrent
干预
Biopsy,Biospecimen Collection,Computed Tomography,Golcadomide
地点
United States
申办方
Nathan Denlinger
正在招募 Phase 2 生物制剂药物放疗
clinicaltrials.gov NCT05805605

Allo HSCT Using RIC and PTCy for Hematological Diseases

适用疾病
Acute Myelogenous Leukemia;Acute Lymphocytic Leukemia;Biphenotypic Acute Leukemia
干预
Peripheral Blood Stem Cell Transplant,Allopurinol 300 MG,Fludarabine,Cyclophosphamide
地点
United States
申办方
Masonic Cancer Center, University of Minnesota
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06834373

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

适用疾病
Large B-Cell Lymphoma With IRF4 Rearrangement;Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma;Recurrent ALK-Positive Large B-Cell Lymphoma
干预
Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy,Chimeric Antigen Receptor T-Cell Therapy
地点
United States
申办方
Mayo Clinic
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06905509

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements
干预
Autologous Hematopoietic Stem Cell Transplantation,Carboplatin,Cytarabine,Dexamethasone
地点
United States
申办方
University of California, Davis
正在招募 Phase 3 药物其他手术/操作
clinicaltrials.gov NCT06724237

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

适用疾病
Anaplastic Large Cell Lymphoma, ALK-Negative;Follicular Helper T-Cell Lymphoma;Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type
干预
Autologous Hematopoietic Stem Cell Transplantation,Best Practice,Biospecimen Collection,Bone Marrow Aspiration
地点
United States
申办方
Eastern Cooperative Oncology Group
即将招募 Phase 1 生物制剂药物
clinicaltrials.gov NCT07024147

JWCAR239 in Patients With B Cell Non-Hodgkin Lymphoma

适用疾病
B-Cell Non-Hodgkin Lymphoma;Large B Cell Diffuse Lymphoma;Follicular Lymphoma
干预
JWCAR239,Fludarabine,Cyclophosphamide
地点
China
申办方
Peking University Cancer Hospital & Institute
正在招募 Phase 1, Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06536049

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Recurrent Grade 3b Follicular Lymphoma;Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
干预
Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
Yazeed Sawalha
正在招募 Phase 3 药物
clinicaltrials.gov NCT06561048

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

适用疾病
Peripheral T-Cell Lymphoma, Not Otherwise Specified;Angioimmunoblastic T-cell Lymphoma;Follicular T-Cell Lymphoma
干预
Soquelitinib,Belinostat,Pralatrexate
地点
United States,Australia,Canada
申办方
Corvus Pharmaceuticals, Inc.
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT07042438

Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements;Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
干预
Axicabtagene Ciloleucel,Biospecimen Collection,Chemotherapy,Fecal Microbiota Transplantation
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT03125642

Auto Stem Cell Transplant for Lymphoma Patients

适用疾病
Non-Hodgkin Lymphoma;Hodgkin Lymphoma
干预
Etoposide,BCNU,AraC,Melphalan
地点
United States
申办方
Masonic Cancer Center, University of Minnesota
正在招募 Phase 2 药物
clinicaltrials.gov NCT06550141

Emapalumab Prevention of CAR-T Cell Associated Toxicities

适用疾病
Large B-cell Lymphoma;Relapsed Non-Hodgkin Lymphoma;Refractory Non-Hodgkin Lymphoma
干预
Emapalumab,Cyclophosphamide,Fludarabine Phosphate,Axicabtagene Ciloleucel
地点
United States
申办方
Marcela V. Maus, M.D.,Ph.D.
正在招募 Phase 3 药物
clinicaltrials.gov NCT06149286

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

适用疾病
Relapsed/Refractory Follicular Lymphoma;Relapsed/Refractory Marginal Zone Lymphoma (R/R MZL)
干预
Odronextamab,Lenalidomide,Rituximab
地点
United States,Australia,Austria,Belgium 等 14 个
申办方
Regeneron Pharmaceuticals
正在招募 EARLY / Phase 1 生物制剂手术/操作放疗
clinicaltrials.gov NCT05800405

Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma;Refractory Diffuse Large B-Cell Lymphoma
干预
Biospecimen Collection,Chimeric Antigen Receptor T-Cell Therapy,Computed Tomography,External Beam Radiation Therapy
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 2 药物
clinicaltrials.gov NCT05249959

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

适用疾病
Relapsed Mantle Cell Lymphoma;Refractory Mantle Cell Lymphoma
干预
Consolidation with ADCT-402 (loncastuximab tesirine) after salvage immunochemotherapy at standard dose (R-BAC, Rituximab - Bendamustine, Ara-C)),Consolidation with ADCT-402 (loncastuximab tesirine) after salvage immunochemotherapy at reduced dose (R-BAC, Rituximab - Bendamustine, Ara-C)
地点
Italy
申办方
Fondazione Italiana Linfomi - ETS
即将招募 Phase 3 药物
clinicaltrials.gov NCT07516093

Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL

适用疾病
B-cell Lymphoma;Chronic Lymphocytic Leukemia;Small Lymphocytic Lymphoma
干预
NX-5948,Pirtobrutinib
地点
未列出
申办方
Nurix Therapeutics, Inc.
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT05884333

Cord Blood Transplant in Adults With Blood Cancers

适用疾病
Acute Myelogenous Leukemia (AML);Acute Lymphoblastic Leukemia (ALL);Chronic Myelogenous Leukemia (CML)
干预
Conditioning Chemotherapy,Cord blood graft
地点
United States
申办方
Memorial Sloan Kettering Cancer Center
正在招募 Phase 3 生物制剂
clinicaltrials.gov NCT04094311

Study of Out of Specification for Tisagenlecleucel

适用疾病
B-cell Acute Lymphoblastic Leukemia;Diffuse Large B-cell Lymphoma
干预
CTL019
地点
Canada,Japan
申办方
Novartis Pharmaceuticals
正在招募 Phase 2, Phase 3 药物
clinicaltrials.gov NCT05595447

Treatment Strategy for Relapsed/Refractory Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma;Refractory Hodgkin Lymphoma;Relapsed Hodgkin's Disease, Adult
干预
Brentuximab Vedotin 50 MG [Adcetris]
地点
Mexico
申办方
Hospital Regional de Alta Especialidad del Bajio
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06918431

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

适用疾病
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative;Lymphoblastic Lymphoma
干预
Asparaginase Erwinia chrysanthemi,Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy
地点
United States
申办方
City of Hope Medical Center
正在招募 阶段未标明 放疗
clinicaltrials.gov NCT04368702

CONFIRM: Magnetic Resonance Guided Radiation Therapy

适用疾病
Gastric Cancer;Invasive Breast Cancer;in Situ Breast Cancer
干预
Viewray MRIdian® Linac
地点
United States
申办方
Brigham and Women's Hospital
正在招募 Phase 2 药物
clinicaltrials.gov NCT06458439

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

适用疾病
Lymphoma, Non-Hodgkin;Relapsed Diffuse Large B Cell Lymphoma;Refractory Diffuse Large B-cell Lymphoma
干预
Epcoritamab
地点
United States
申办方
Abramson Cancer Center at Penn Medicine
正在招募 Phase 1 药物
clinicaltrials.gov NCT04970901

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

适用疾病
B-Cell Non-Hodgkin Lymphoma;Relapsed B-Cell Non-Hodgkin Lymphoma;Refractory B-Cell Non-Hodgkin Lymphoma
干预
Loncastuximab Tesirine,Polatuzumab Vedotin,Glofitamab,Mosunetuzumab
地点
United States,Belgium,Czechia,Italy 等 2 个
申办方
ADC Therapeutics S.A.
即将招募 Phase 2, Phase 3 生物制剂药物手术/操作
clinicaltrials.gov NCT07572123

Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin Lymphoma

适用疾病
Recurrent Classic Hodgkin Lymphoma;Refractory Classic Hodgkin Lymphoma
干预
3-Dimensional Conformal Radiation Therapy,Autologous Hematopoietic Stem Cell Transplantation,Biospecimen Collection,Brentuximab Vedotin
地点
未列出
申办方
National Cancer Institute (NCI)
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05092451

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

适用疾病
B-Cell Lymphoma;Myelodysplastic Syndromes (MDS);Acute Myeloid Leukemia (AML)
干预
Cyclophosphamide,CAR.70/IL15-transduced CB-NK cells,Fludarabine phosphate
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT07439653

A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma

适用疾病
Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
干预
TORL-5-700,TORL-5-700 at MTD/RP2D,TORL-5-700 at MTD/RP2D in combination with another agent
地点
United States
申办方
TORL Biotherapeutics, LLC
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04855695

Avo In R/R And Previously Untreated MCL

适用疾病
Mantle Cell Lymphoma;Refractory Lymphoma
干预
Acalabrutinib,Venetoclax,Obinutuzumab
地点
United States
申办方
Austin I Kim
正在招募 Phase 3 药物
clinicaltrials.gov NCT05645107

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

适用疾病
Hypogammaglobulinemia;Bacterial Infections;B-cell Chronic Lymphocytic Leukemia
干预
Xembify,Placebo
地点
United States,Bosnia and Herzegovina,Bulgaria,Croatia 等 4 个
申办方
Grifols Therapeutics LLC
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT04429438

Multi-CAR-T Cells Targeting B Cell Lymphomas

适用疾病
B Cell Lymphoma (BCL)
干预
4SCAR19 and 4SCAR20/22/70/PSMA/13/79b/GD2
地点
China
申办方
Shenzhen Geno-Immune Medical Institute
正在招募 Phase 1, Phase 2 生物制剂药物
clinicaltrials.gov NCT06090864

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

适用疾病
Hodgkin Lymphoma;Relapse;Refractory
干预
Chemotherapy,Cell infusion
地点
United States
申办方
UNC Lineberger Comprehensive Cancer Center
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT07022964

CD5 CAR T-Cell Therapy for r/r T-cell Lymphomas

适用疾病
T-Cell Non-Hodgkin Lymphoma;T-cell Lymphoma (PTCL and CTCL)
干预
CD5 CAR-T cells infusion
地点
China
申办方
Beijing GoBroad Hospital
正在招募 Phase 2 药物
clinicaltrials.gov NCT06812858

PD-1 Inhibitors Maintenance for cHL Post-autoHCT

适用疾病
Hodgkin Lymphoma
干预
Nivolumab, Pembrolizumab
地点
Kazakhstan,Russia
申办方
St. Petersburg State Pavlov Medical University
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT03829540

CD4CAR for CD4+ Leukemia and Lymphoma

适用疾病
T-cell Lymphoma;T-cell Leukemia
干预
CD4CAR
地点
United States
申办方
Huda Salman
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT04840602

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

适用疾病
Lymphoplasmacytic Lymphoma;Waldenstrom Macroglobulinemia
干预
Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT06445803

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

适用疾病
Acute Lymphoblastic Leukemia, in Relapse;Acute Lymphoblastic Leukemia With Failed Remission;B-cell Lymphoma Refractory
干预
KQ-2002 CAR-T cells (CD19/CD22 CAR T-Cells)
地点
China
申办方
Rong Tao
即将招募 Phase 2 药物
clinicaltrials.gov NCT06665217

G-Pola-ZLP in Diffuse Large B-Cell Lymphoma

适用疾病
Diffuse Large B-Cell Lymphoma
干预
Glofitamab, Polatuzumab Vedotin, Zanubrutinib, Lenalidomide and Prednisone as Induction Therapy
地点
未列出
申办方
Navy General Hospital, Beijing
正在招募 Phase 2 生物制剂药物其他
clinicaltrials.gov NCT02727803

Personalized NK Cell Therapy in CBT

适用疾病
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;Acute Biphenotypic Leukemia;Acute Lymphoblastic Leukemia
干预
Allogeneic Natural Killer Cell Line NK-92,Anti-Thymocyte Globulin,Busulfan,Clofarabine
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT05674175

Co-administration of CART22-65s and huCART19 for B-ALL

适用疾病
B-cell Acute Lymphoblastic Leukemia;B Lineage Lymphoblastic Lymphoma
干预
Autologous, humanized anti-CD22 CAR T cell therapy (CART22-65s),Autologous, humanized anti-CD19 CAR T cell therapy (huCART19)
地点
United States
申办方
Stephan Grupp MD PhD
正在招募 Phase 1 药物
clinicaltrials.gov NCT06393738

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

适用疾病
Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL);Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)
干预
ARV-393,Glofitamab
地点
United States,Canada,Denmark,Spain
申办方
Arvinas Inc.
即将招募 Phase 2 药物
clinicaltrials.gov NCT06701344

Go-CHOP in de Novo Intestinal T-cell Lymphoma Patients

适用疾病
Enteropathy Associated T Cell Lymphoma
干预
Go-CHOP (Golidocitinib plus Cyclophosphamide, vincristine, doxorubicin and prednisone),Golidocitinib
地点
未列出
申办方
Ruijin Hospital
正在招募 Phase 2 生物制剂药物其他
clinicaltrials.gov NCT07097363

Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma

适用疾病
B-Cell Non-Hodgkin Lymphoma;Burkitt Lymphoma;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
干预
Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
University of Washington
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT06508463

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

适用疾病
Peripheral T Cell Lymphoma;Relapsed Peripheral T-Cell Lymphoma;Peripheral T-Cell Lymphoma, Not Otherwise Specified
干预
Biopsy,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
Mayo Clinic
即将招募 Phase 1 药物
clinicaltrials.gov NCT07603479

A Phase I Study of JL19001 Injection Alone or in Combination With Standard Therapy in Patients With Advanced Solid Tumors or Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

适用疾病
Malignancies;Solid Malignant Tumor;NHL (Non-Hodgkin Lymphoma)
干预
JL19001, subcutaneous injection, 1 μg/kg,JL19001, subcutaneous injection, 5 μg/kg,JL19001, subcutaneous injection,10 μg/kg,JL19001, subcutaneous injection,15 μg/kg
地点
未列出
申办方
Jecho Biopharmaceuticals Co., Ltd.
正在招募 Phase 2 药物
clinicaltrials.gov NCT04510636

Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma

适用疾病
Classical Hodgkin Lymphoma;Relapsed Cancer;Refractory Cancer
干预
Pembrolizumab,Bendamustine Hydrochloride
地点
Canada
申办方
University Health Network, Toronto
正在招募 Phase 1 药物
clinicaltrials.gov NCT06060782

Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine

适用疾病
Burkitt Lymphoma;Lymphoblastic Lymphoma, Adult;Acute Lymphoblastic Leukemia, Adult
干预
Thiotepa, cyclophosphamide, cladribine, and cytarabine conditioning regimen
地点
China
申办方
Fifth Affiliated Hospital, Sun Yat-Sen University
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT06874946

Nanobody-Based Anti-CD5 CAR-T for Relapsed/Refractory T-ALL/NHL

适用疾病
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma;T - Cell Lymphoma;PTCL
干预
CD5-targeted CAR-T cells
地点
China
申办方
Peking University People's Hospital
即将招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT07583810

Non-covalent BTK Inhibitor Nemtabrutinib in Combination With the CD20 Monoclonal Antibody Rituximab for the Treatment of Marginal Zone Lymphoma

适用疾病
Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma;Gastric Mucosa-Associated Lymphoid Tissue Lymphoma;Marginal Zone Lymphoma
干预
Biopsy Procedure,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 2 药物
clinicaltrials.gov NCT06508099

Vitamin A and D Supplementation in Allogeneic HCT

适用疾病
Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Biphenotypic Acute Leukemia
干预
Vitamin A,Vitamin D3
地点
Russia
申办方
St. Petersburg State Pavlov Medical University
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT05989204

TmCD19-IL18 in CD19+ Cancers

适用疾病
Non Hodgkin Lymphoma
干预
TmCD19-IL18
地点
United States
申办方
University of Pennsylvania
即将招募 Phase 1 生物制剂
clinicaltrials.gov NCT07113496

RN1201injection for Relapsed/Refractory CD19+/BCMA+ Hematologic Malignancies

适用疾病
Relapsed or Refractory B-cell Hematologic Malignancies;B-cell Acute Lymphoblastic Leukemia (B-ALL);Multiple Myeloma (MM)
干预
Allogeneic CAR-T
地点
China
申办方
The First Affiliated Hospital with Nanjing Medical University
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT04664179

EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma

适用疾病
EBV-Related Hodgkin Lymphoma;EBV-Related Lymphoproliferative Disorder;EBV Related Non-Hodgkin's Lymphoma
干预
Dose Level 1A: 2 x 10^7 cells/m2,Dose Level 2A: 6 x 10^7 cells/m2,Dose Level 2B: 6 x 10^7 cells/m2,Dose Level 3B: 2 x 10^8 cells/m2
地点
United States
申办方
Baylor College of Medicine
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07623850

A Phase I Study of JLM019 Injection

适用疾病
Advanced Solid Tumor (Phase 1);Hodgkin Lymphoma;Non-Hodgkin Lymphoma
干预
JLM019 Injection
地点
China
申办方
Jecho Biopharmaceuticals Co., Ltd.
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07451054

CD45BE-HSPC + CART-45 Cells

适用疾病
B-Cell Non-Hodgkin Lymphoma (NHL);Richter's Transformation;T-Cell Non-Hodgkin Lymphoma
干预
CART-45 cells,CD45BE-HSPC
地点
United States
申办方
University of Pennsylvania
正在招募 Phase 2, Phase 3 药物
clinicaltrials.gov NCT07168980

Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents

适用疾病
Mature B-cell Non-Hodgkin Lymphoma
干预
Cyclophosphamide, Vincristine, Cytarabine, Doxorubincin, Prednisone,Drug: Ifosphamide, Etoposide, Methotrexate, Vincristine, Prednisone,Cyclophosphamide, Vincristine, Cytarabine, Doxorubincin, Prednisone,Ifosphamide, Etoposide, Methotrexate, Vincristine, Prednisone
地点
China
申办方
Children's Cancer Group, China
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT03017820

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

适用疾病
B-Cell Non-Hodgkin Lymphoma;Histiocytic and Dendritic Cell Neoplasm;Myelodysplastic Syndrome
干预
Biopsy Procedure,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
Mayo Clinic
即将招募 Phase 1 药物
clinicaltrials.gov NCT04419909

Retreatment With CTL019/CTL119

适用疾病
Lymphoma, B-Cell
干预
CD19 redirected autologous T cells (CTL019 or CTL119 cells)
地点
United States
申办方
University of Pennsylvania
正在招募 Phase 2 药物
clinicaltrials.gov NCT05963347

Go-CHOP as the Frontline Therapy for PTCL

适用疾病
Peripheral T Cell Lymphoma
干预
Golidocitinib,CHOP Regimen
地点
China
申办方
Henan Cancer Hospital
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT07166419

Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia

适用疾病
Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive;Recurrent Acute Lymphoblastic Leukemia;Recurrent Chronic Lymphocytic Leukemia
干预
Autologous Anti-CD19/CD20/CD22 CAR T-cells,Biospecimen Collection,Bone Marrow Aspiration,Bone Marrow Biopsy
地点
United States
申办方
Ohio State University Comprehensive Cancer Center
正在招募 Phase 1 药物手术/操作
clinicaltrials.gov NCT05755087

Tegavivint for Treating Patients With Relapsed or Refractory Large B-Cell Lymphoma

适用疾病
Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type;Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type;Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
干预
Biospecimen Collection,Computed Tomography,Positron Emission Tomography,Tegavivint
地点
United States
申办方
Lapo Alinari
正在招募 Phase 4 药物放疗
clinicaltrials.gov NCT03500133

Pediatric Hodgkin Lymphoma Treatment Trial With Low Cumulative Doses of Chemotherapy Agents and Reduced Radiation.

适用疾病
Pediatric Hodgkin's Disease
干预
No radiotherapy if CR at the end of chemotherapy.,Low risk with complete early response after two cycles of ABVD chemotherapy schedule. Only one more ABVD course is delivered.,Low risk with partial remisssion after 4 cycles of ABVD chemotherapy schedule. Two ESHAP courses are delivered.,IN 30Gy RT in case of PR at the end of chemotherapy
地点
Argentina
申办方
Hospital JP Garrahan
正在招募 Phase 1 生物制剂手术/操作
clinicaltrials.gov NCT05432635

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

适用疾病
B-Cell Non-Hodgkin Lymphoma;Diffuse Large B-Cell Lymphoma;Mantle Cell Lymphoma
干预
Anti-CD19-CAR CMV-specific T-lymphocytes,Autologous Hematopoietic Stem Cell Transplantation,Multi-peptide CMV-Modified Vaccinia Ankara Vaccine,Myeloablative Conditioning
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06739265

Golidocitinib Plus CHOP in Newly Diagnosed PTCL

适用疾病
Peripheral T-cell Lymphoma
干预
Golidocitinib plus CHOP
地点
China
申办方
Peking Union Medical College Hospital
正在招募 Phase 4 药物
clinicaltrials.gov NCT05518383

B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021

适用疾病
Non-hodgkin Lymphoma,B Cell;Burkitt Lymphoma;Primary Mediastinal Lymphoma
干预
Cyclophosphamide, Cytarabine, Dexamethasone, Etoposide, Ifosfamide, Methotrexate,Cyclophosphamide, Cytarabine, Dexamethasone, Etoposide, Ifosfamide, Methotrexate, Vincristine,Cyclophosphamide, Cytarabine, Dexamethasone, Doxorubicin hydrochloride, Etoposide, Ifosfamide, Methotrexate, vincristine,Cyclophosphamide , Cytarabine, Dexamethasone, Doxorubicin hydrochloride, Etoposide, Ifosfamide, Methotrexate, Vincristine, Сarboplatine, CCNU/ BCNU, Melphalan, Idarubicin
地点
Russia
申办方
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06925464

CD7 CAR T-Cell Therapy for r/r T-cell Lymphomas

适用疾病
T-Cell Non-Hodgkin Lymphoma;T-cell Lymphoma (PTCL and CTCL)
干预
CD7 CAR-T cells infusion
地点
China
申办方
Beijing GoBroad Hospital
即将招募 Phase 2 药物
clinicaltrials.gov NCT07279584

Golidocitinib Combined With GemOx in RR PTCL

适用疾病
Peripheral T-cell Lymphomas (PTCL)
干预
golidocitinib,GEMOX
地点
未列出
申办方
Ruijin Hospital
正在招募 EARLY / Phase 1 生物制剂药物
clinicaltrials.gov NCT04139304

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

适用疾病
Plasmablastic Lymphoma;Ann Arbor Stage I Diffuse Large B-Cell Lymphoma;Ann Arbor Stage II Diffuse Large B-Cell Lymphoma
干预
Cyclophosphamide,Daratumumab,Doxorubicin,Doxorubicin Hydrochloride
地点
United States
申办方
AIDS Malignancy Consortium
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT06421948

Linperlisib Combined With Chidamide in Patients With PTCL

适用疾病
Peripheral T-cell Lymphoma
干预
Linperlisib and chidamide,Linperlisib and chidamide,Linperlisib and chidamide,cyclophosphamide, doxorubicin/epirubicin, vincristine, and prednisone
地点
China
申办方
Yanyan Liu
正在招募 Phase 2 生物制剂其他手术/操作
clinicaltrials.gov NCT05886036

Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial

适用疾病
Nodular Lymphocyte Predominant B-Cell Lymphoma;Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma;Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma
干预
Biopsy Procedure,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States,Canada
申办方
National Cancer Institute (NCI)
即将招募 Phase 1 生物制剂
clinicaltrials.gov NCT06385522

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

适用疾病
NHL;Cutaneous T Cell Lymphoma;Peripheral T-cell Lymphoma
干预
BITR2101
地点
未列出
申办方
Boston Immune Technologies and Therapeutics
正在招募 Phase 2 药物
clinicaltrials.gov NCT06190067

Azacitidine Plus PD-1 Therapy for R/R Hodgkin Lymphoma

适用疾病
Relapsed Classic Hodgkin Lymphoma;Refractory Classic Hodgkin Lymphoma
干预
Azacitidine Plus PD-1 therapy
地点
China
申办方
Navy General Hospital, Beijing
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT01555892

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

适用疾病
Hodgkin's Disease;Non-Hodgkin's Lymphoma;Lymphoproliferative Disease
干预
EBV-specific T cells: A,EBV-specific T cells: B
地点
United States
申办方
Baylor College of Medicine
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT07523555

Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies

适用疾病
Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia;Relapsed/Refractory B-cell Non-Hodgkin Lymphoma or CLL/SLL;Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia
干预
Autologous CD19/CD22 dual-target CAR-T module,Autologous CD19/CD20 dual-target CAR-T module,Autologous BCMA/CD19 dual-target CAR-T module,Autologous BCMA/CD38 dual-target CAR-T module
地点
China
申办方
Beijing Biotech
正在招募 阶段未标明 药物
clinicaltrials.gov NCT07248163

Universal CAR-T Cell Therapy for NHL

适用疾病
Non-hodgkin Lymphoma,B Cell
干预
BRL-301
地点
China
申办方
Bioray Laboratories
正在招募 Phase 2 药物
clinicaltrials.gov NCT04906096

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

适用疾病
Primary Central Nervous System Lymphoma;Non-Hodgkin Lymphoma of Extranodal Site
干预
PAXALISIB
地点
United States
申办方
Lakshmi Nayak, MD
正在招募 Phase 2 药物
clinicaltrials.gov NCT07283822

Amping up With PemJAK

适用疾病
Non-Hodgkin Lymphoma;Hodgkin Disease Lymphoma;Non-Hodgkin Lymphoma Refractory/ Relapsed
干预
Ruxolitinib,Pembrolizumab
地点
United States
申办方
Seda S. Tolu
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04068597

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

适用疾病
Haematological Malignancy;Acute Myeloid Leukemia;Non Hodgkin Lymphoma
干预
CCS1477,Pomalidomide,Dexamethasone,Azacitidine
地点
United States,France,Spain,Sweden 等 1 个
申办方
CellCentric Ltd.
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT04083495

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

适用疾病
Peripheral T Cell Lymphoma
干预
ATLCAR.CD30 T cells,Bendamustine,Fludarabine,Cyclophosphamide
地点
United States
申办方
UNC Lineberger Comprehensive Cancer Center
正在招募 Phase 3 药物放疗
clinicaltrials.gov NCT04685616

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma
干预
Involved site radiotherapy,Doxorubicin,Bleomycin,Brentuximab vedotin
地点
United States,Australia,Belgium,Canada 等 8 个
申办方
University College, London
即将招募 EARLY / Phase 1 药物
clinicaltrials.gov NCT07048353

CD30 CAR-T in the Treatment of CD30 Positive Lymphoma

适用疾病
Lymphoma;B Cell Lymphoma;CD30+ Peripheral T-cell Lymphoma
干预
chimeric antigen receptor gene modified T cells
地点
China
申办方
Shandong Qilu Cell Therapy Engineering Technology Co., Ltd
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06839053

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

适用疾病
Chronic Lymphocytic Leukemia;Mantle Cell Lymphoma;Recurrent Chronic Lymphocytic Leukemia
干预
Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography,Gastrointestinal Endoscopy
地点
United States
申办方
Fred Hutchinson Cancer Center
正在招募 Phase 2 药物手术/操作放疗
clinicaltrials.gov NCT05031897

Two Step Haplo With Radiation Conditioning

适用疾病
Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Adult T-Cell Leukemia/Lymphoma
干预
Fludarabine,Total-Body Irradiation,Donor Lymphocyte Infusion,Cyclophosphamide
地点
United States
申办方
Thomas Jefferson University
正在招募 Phase 2 药物
clinicaltrials.gov NCT05909059

CAR T-cell Therapy in Patients With Renal Dysfunction

适用疾病
Non-hodgkin Lymphoma,B Cell;Multiple Myeloma;Acute Lymphoblastic Leukemia, Adult
干预
Fludarabine,Cyclophosphamide
地点
United States
申办方
Northside Hospital, Inc.
正在招募 Phase 1 生物制剂手术/操作
clinicaltrials.gov NCT05801913

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma

适用疾病
High Grade B-Cell Non-Hodgkin's Lymphoma;Intermediate Grade B-Cell Non-Hodgkin's Lymphoma;Recurrent B-Cell Non-Hodgkin Lymphoma
干预
Anti-CD19-CAR CMV-specific T-lymphocytes,Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT05873712

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

适用疾病
Recurrent Transformed Chronic Lymphocytic Leukemia;Refractory Transformed Chronic Lymphocytic Leukemia;Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma
干预
Biospecimen Collection,Bone Marrow Biopsy,Computed Tomography,Cyclophosphamide
地点
United States
申办方
Aseel Alsouqi
即将招募 Phase 1 药物手术/操作
clinicaltrials.gov NCT07332507

Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma

适用疾病
Recurrent Plasmablastic Lymphoma;Refractory Plasmablastic Lymphoma
干预
Biospecimen Collection,Computed Tomography,Positron Emission Tomography,Teclistamab
地点
未列出
申办方
National Cancer Institute (NCI)
正在招募 Phase 2 药物
clinicaltrials.gov NCT04378647

BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant

适用疾病
Hodgkin Lymphoma, Adult
干预
Induction with Brentuximab vedotin (BV),Induction without Brentuximab Vedotin,Consolidation with Brentuximab Vedotin
地点
Spain
申办方
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05675813

Genotype-guided Treatment in Newly Diagnosed PTCL

适用疾病
Peripheral T Cell Lymphoma
干预
CHOP+selinexor+5-Azacitidine,CHOP+duvelisib+5-Azacitidine,CHOP+chidamide+tislelizumab,standard CHOP
地点
China
申办方
Ruijin Hospital
正在招募 Phase 2, Phase 3 药物
clinicaltrials.gov NCT06756152

Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis

适用疾病
Biphenotypic Acute Leukemia;Acute Lymphoblastic Leukemia;Myeloblastic Leukemia
干预
Conditioning regimen: Treosulfan 42 g/m2/course or total body irradiation 12 Gray/course, Etoposide 60 mg/kg , Fludarabine 150
地点
Russia
申办方
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
正在招募 Phase 1 生物制剂药物
clinicaltrials.gov NCT07055477

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

适用疾病
Relapsed and/or Refractory Mature T Cell Malignancy;Peripheral T-Cell Lymphoma;Angioimmunoblastic T-cell Lymphoma
干预
Cyclophosphamide,Fludarabine,Autologous CCR4 CAR T cells
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 2 药物
clinicaltrials.gov NCT06793189

MZL-IPI Risk-adapted Targeted Therapy in Untreated MZL

适用疾病
Marginal Zone Lymphoma(MZL)
干预
Obinutuzumab and Orelabrutinib,Obinutuzumab, Orelabrutinib and Lenalidomide,Orelabrutinib,Orelabrutinib
地点
China
申办方
Ruijin Hospital
即将招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04856137

A Phase I/II Study of Diffuse Large B-cell Lymphoma

适用疾病
Refractory Diffuse Large B-cell Lymphoma
干预
Rituximab Paclitaxel Ruxolitinib
地点
未列出
申办方
National Health Research Institutes, Taiwan
正在招募 Phase 2 生物制剂其他手术/操作
clinicaltrials.gov NCT06238648

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

适用疾病
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;Primary Mediastinal Large B-Cell Lymphoma;Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
干预
Biopsy,Biospecimen Collection,Computed Tomography,Epcoritamab
地点
United States
申办方
Academic and Community Cancer Research United
即将招募 Phase 2 器械药物手术/操作
clinicaltrials.gov NCT07021989

ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma, Adult;Refractory Hodgkin Lymphoma;Classic Hodgkin Lymphoma
干预
Pembrolizumab,Non-investigational, involved site radiotherapy (ISRT),Gemcitabine,Vinorelbine
地点
United States
申办方
Michael Spinner, MD
正在招募 Phase 2 药物
clinicaltrials.gov NCT07002216

BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma;Advanced Hodgkin Lymphoma
干预
Brentuximab Vedotin,Etoposide,Cyclophosphamide,Doxorubicin
地点
United States
申办方
University of Miami
正在招募 Phase 2 药物
clinicaltrials.gov NCT07081022

JS203 Combination Regimens in B-Cell Non-Hodgkin's Lymphoma

适用疾病
B-cell Non-Hodgkin's Lymphoma
干预
JS203 in combination with gemcitabine and oxaliplatin,JS203 in combination with ifosfamide, carboplatin and etoposide,JS203 in combination with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone,JS203 combined with lenalidomide
地点
China
申办方
Shanghai Junshi Bioscience Co., Ltd.
正在招募 阶段未标明 药物
clinicaltrials.gov NCT06069830

PET and EBV DNA-directed Therapy for Localized Nasal Extranodal NK/T Cell Lymphoma

适用疾病
NK-T-Cell Lymphoma, Extranodal
干预
4 cycles of ESA regimen with sandwiched radiotherapy,2 cycles of ESA regimen sequential radiotherapy and 2 cycles of PD-1 monoclonal antibody combined with pegaspargase,2 cycles of ESA regimen, 2 cycles of PD-1 monoclonal antibody and concurrent radiotherapy, 2 cycles of PD-1 monoclonal antibody combined with pegaspargase
地点
China
申办方
Ruijin Hospital
正在招募 阶段未标明 生物制剂
clinicaltrials.gov NCT06866873

CD-19 CAR-T Cell for Pediatric ALL or Lymphoma

适用疾病
Lymphoma, B-Cell;Acute Lymphoblastic Leukemia, Pediatric
干预
CAR-T
地点
Hong Kong
申办方
Hong Kong Children's Hospital
即将招募 Phase 1 生物制剂
clinicaltrials.gov NCT07616089

Phase I Study of FXS0683 in the Treatment of Blood Tumors

适用疾病
B-Cell Lymphoma;Acute Myeloid Leukemia;Myelodysplastic Syndromes
干预
FXS0683
地点
China
申办方
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT06059391

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

适用疾病
Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Chronic Lymphocytic Leukemia
干预
Allogeneic Hematopoietic Stem Cell Transplantation,Biospecimen Collection,Granulocyte Colony-Stimulating Factor,Hematopoietic Cell Transplantation Conditioning Regimen
地点
United States
申办方
City of Hope Medical Center
正在招募 Phase 2 诊断检测药物
clinicaltrials.gov NCT06377566

A Study of BV-AVD in People With Bulky Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma
干预
Brentuximab vedotin,Doxorubicin,Vinblastine,Dacarbazine
地点
United States
申办方
Memorial Sloan Kettering Cancer Center
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT06486051

A Study of WZTL-002 CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

适用疾病
Large B-cell Lymphoma;Diffuse Large B-Cell Lymphoma, Not Otherwise Specified;Primary Mediastinal Large B-cell Lymphoma (PMBCL)
干预
Fludarabine,Cyclophosphamide,WZTL-002 CAR T-cells
地点
New Zealand
申办方
Malaghan Institute of Medical Research
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04544592

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

适用疾病
B-cell Acute Lymphoblastic Leukemia;B-cell Non Hodgkin Lymphoma
干预
CD19CAR-CD3Zeta-4-1BB-Expressing Autologous T-Lymphocyte Cells
地点
United States
申办方
University of Colorado, Denver
正在招募 Phase 1, Phase 2 生物制剂药物其他
clinicaltrials.gov NCT01371630

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

适用疾病
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1;B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative;Burkitt-Like Lymphoma With 11q Aberration
干预
Blinatumomab,Cyclophosphamide,Cytarabine,Dexamethasone
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 阶段未标明 药物
clinicaltrials.gov NCT07211048

Anti CD19 Gene Therapy for B-cell Lymphoma

适用疾病
B-cell Lymphoma
干预
Anti-CD19 gene injection
地点
China
申办方
Anhui Provincial Hospital
正在招募 EARLY / Phase 1 器械药物
clinicaltrials.gov NCT06398457

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

适用疾病
Hematologic Malignancy;Bone Marrow Transplant Rejection;Acute Myeloid Leukemia (AML)
干预
Darzalex Faspro (Daratumumab and hyaluronidase-fihj),JH-DSA Semi-Quant Screen and Response Score
地点
United States
申办方
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
正在招募 Phase 2 药物
clinicaltrials.gov NCT07013565

Chemoimmunotherapy for ALK+ Relapsed/Refractory ALCL

适用疾病
Anaplastic Large Cell Lymphoma, ALK-Positive
干预
Vinblastine (Velban),Brentuximab vedotin (Adcetris),Nivolumab (Opdivo)
地点
United States
申办方
New York Medical College
正在招募 Phase 2 药物
clinicaltrials.gov NCT06984146

Nivo40-AVD for Advanced Classic Hodgkin Lymphoma

适用疾病
Hodgkin Lymphoma, Adult
干预
Nivolumab,Doxorubicin,Vinblastine,Dacarbazine
地点
Russia
申办方
National Medical Research Radiological Centre of the Ministry of Health of Russia
正在招募 Phase 2 器械药物
clinicaltrials.gov NCT05680558

Photopheresis in Early-stage Mycosis Fungoides

适用疾病
Cutaneous T Cell Lymphoma;Mycosis Fungoides
干预
UVADEX® (methoxsalen) Sterile Solution in conjunction with the THERAKOS® CELLEX Photopheresis,THERAKOS® CELLEX photopheresis system
地点
United States
申办方
Columbia University
正在招募 Phase 1 药物手术/操作
clinicaltrials.gov NCT06223542

Studying TAK-243 in Patients With Advanced Cancer

适用疾病
Advanced Lymphoma;Advanced Malignant Solid Neoplasm;Indolent Non-Hodgkin Lymphoma
干预
Biopsy Procedure,Biospecimen Collection,Computed Tomography,Echocardiography Test
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 2 生物制剂药物放疗
clinicaltrials.gov NCT07566377

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

适用疾病
Acute Myelogenous Leukemia;Acute Lymphoblastic Leukemia;Myelodysplastic Syndromes
干预
Cord Blood Units,Total Body Irradiation,Cyclophosphamide,Fludarabine
地点
United States
申办方
Memorial Sloan Kettering Cancer Center
正在招募 Phase 1 生物制剂药物手术/操作
clinicaltrials.gov NCT04892277

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

适用疾病
Recurrent B-Cell Non-Hodgkin Lymphoma;Recurrent Chronic Lymphocytic Leukemia;Recurrent Small Lymphocytic Lymphoma
干预
Autologous Anti-CD19 CAR-expressing T-lymphocytes IC19/1563,Bendamustine,Biospecimen Collection,Bone Marrow Aspiration
地点
United States
申办方
Mayo Clinic
正在招募 Phase 2 生物制剂药物
clinicaltrials.gov NCT03136146

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia

适用疾病
Recurrent Acute Lymphoblastic Leukemia;Recurrent Adult Lymphoblastic Lymphoma;Recurrent Burkitt Leukemia
干预
Bortezomib,Clofarabine,Cyclophosphamide,Dexamethasone
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 Phase 1 药物
clinicaltrials.gov NCT05010005

A Study of Ruxolitinib and Duvelisib in People With Lymphoma

适用疾病
T-cell Lymphomas;NK-Cell Lymphomas;T-cell Prolymphocytic Leukemia
干预
Ruxolitinib,Duvelisib
地点
United States
申办方
Memorial Sloan Kettering Cancer Center
正在招募 Phase 2 生物制剂药物手术/操作
clinicaltrials.gov NCT02981628

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

适用疾病
Recurrent B Acute Lymphoblastic Leukemia;Recurrent B Lymphoblastic Lymphoma;Refractory B Acute Lymphoblastic Leukemia
干预
Asparaginase Erwinia chrysanthemi,Biospecimen Collection,Bone Marrow Aspiration and Biopsy,Calaspargase Pegol
地点
United States,Puerto Rico
申办方
Children's Oncology Group
正在招募 Phase 1, Phase 2 生物制剂药物
clinicaltrials.gov NCT05554939

Allogenic CD19-targeting CAR-γδT Cell Therapy in R/R NHL

适用疾病
Non Hodgkin's Lymphoma
干预
Allogenic CD19 CAR-γδT cell,Fludarabine,Cyclophosphamide
地点
China
申办方
Chinese PLA General Hospital
正在招募 Phase 1, Phase 2 药物手术/操作
clinicaltrials.gov NCT04870944

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

适用疾病
Diffuse Midline Glioma, H3 K27-Altered;Metastatic Malignant Neoplasm in the Central Nervous System;Recurrent Diffuse Intrinsic Pontine Glioma
干预
Biospecimen Collection,Bone Marrow Aspirate,Bone Marrow Biopsy,Echocardiography Test
地点
United States,Australia
申办方
Children's Oncology Group
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07108868

A Phase I Dose Finding Study of MB-CART2219.1

适用疾病
Lymphoma;CLL;Acute Lymphoblastic Leukemia, Pediatric
干预
CAR-T cells targeting CD19 and CD22
地点
Germany
申办方
University Hospital Tuebingen
正在招募 Phase 2 药物手术/操作
clinicaltrials.gov NCT05934448

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

适用疾病
Primary Mediastinal Large B-cell Lymphoma (PMBCL);Primary Mediastinal Large B Cell Lymphoma;Primary Mediastinal Large B-Cell Lymphoma Refractory
干预
Pembrolizumab,Lymphodepletion Chemotherapy,Chimeric Antigen Receptor (CAR) Therapy Infusion,Leukapheresis
地点
United States
申办方
Jennifer Crombie, MD
正在招募 Phase 2 药物
clinicaltrials.gov NCT06561074

A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)

适用疾病
T-cell Acute Lymphoblastic Leukemia;T-Cell Lymphoblastic Lymphoma
干预
Decitabine,Venetoclax,Calaspargase pegol-mknl
地点
United States
申办方
M.D. Anderson Cancer Center
正在招募 Phase 2 药物
clinicaltrials.gov NCT04560322

Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL

适用疾病
Chronic Lymphocytic Leukemia;Small Lymphocytic Lymphoma
干预
Venetoclax,Obinutuzumab,Acalabrutinib
地点
United States
申办方
Massachusetts General Hospital
正在招募 Phase 3 药物
clinicaltrials.gov NCT06943872

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

适用疾病
Chronic Lymphocytic Leukemia;Small Lymphocytic Lymphoma
干预
Sonrotoclax,Obinutuzumab,Rituximab,Venetoclax
地点
United States,Argentina,Australia,Austria 等 17 个
申办方
BeOne Medicines
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05745714

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

适用疾病
Acute Lymphoblastic Leukemia, in Relapse;Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent;Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent
干预
Ruxolitinib,Venetoclax,Dexamethasone,Cyclophosphamide
地点
Austria,Belgium,Denmark,Finland 等 10 个
申办方
Princess Maxima Center for Pediatric Oncology
正在招募 Phase 1 药物
clinicaltrials.gov NCT05292664

Venetoclax Basket Trial for High Risk Hematologic Malignancies

适用疾病
Myelodysplastic Syndromes, de Novo;Myelodysplastic Syndromes, Secondary;Myelodysplastic Syndromes, Previously Treated
干预
Venetoclax,Azacitidine,Cytarabine,Methotrexate
地点
United States
申办方
Andrew E. Place, MD
即将招募 Phase 1 药物
clinicaltrials.gov NCT07511426

U96-CAR-T-Cells For R/R B-ALL

适用疾病
Relapsed or Refractory B Cell Leukemia and Lymphoma
干预
U96
地点
China
申办方
The First Affiliated Hospital of Soochow University
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT04421560

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

适用疾病
Primary Central Nervous System Lymphoma;Recurrent Cancer;Refractory Cancer
干预
Ibrutinib,Pembrolizumab,Rituximab
地点
United States
申办方
Dana-Farber Cancer Institute
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05658640

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies

适用疾病
Acute Lymphoblastic Leukemia, in Relapse;Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent;Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent
干预
Trametinib,Dexamethasone,Cyclophosphamide,Cytarabine
地点
Austria,Belgium,Denmark,Finland 等 11 个
申办方
Princess Maxima Center for Pediatric Oncology
正在招募 Phase 1 生物制剂手术/操作
clinicaltrials.gov NCT06672705

Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative Disorders

适用疾病
Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder;EBV-Related Post-Transplant Lymphoproliferative Disorder;Recurrent Monomorphic Post-Transplant Lymphoproliferative Disorder
干预
Biopsy,Biospecimen Collection,Computed Tomography,Epcoritamab
地点
United States
申办方
Timothy Voorhees
正在招募 Phase 2 药物
clinicaltrials.gov NCT06742463

VHAG in Treating R/R T-ALL/LBL

适用疾病
Acute T Lymphpblastic Leukemia/Lymphoma
干预
Venetoclax,homoharringtonine,Cytarabine (Ara-C),G-CSF
地点
China
申办方
First Affiliated Hospital of Zhejiang University
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT05751044

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

适用疾病
Acute Lymphoblastic Leukemia;Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent;Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent
干预
Dasatinib,Venetoclax,Dexamethasone,Cyclophosphamide
地点
Austria,Belgium,Denmark,Finland 等 10 个
申办方
Princess Maxima Center for Pediatric Oncology
正在招募 Phase 1 生物制剂药物
clinicaltrials.gov NCT05631886

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

适用疾病
Solid Tumor, Adult;Lymphoma;EphA2 Overexpression
干预
TP53-EphA-2-CAR-DC,Abraxane,Cyclophosphamide,anti-PD-1 antibody
地点
China
申办方
Chinese PLA General Hospital
正在招募 Phase 1 生物制剂药物
clinicaltrials.gov NCT05963217

Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL

适用疾病
Relapsed or Refractory CD19+ B-cell Lymphoma;Relapsed or Refractory Chronic Lymphocytic Leukemia;Relapsed or Refractory Small Lymphocytic Lymphoma
干预
TBI-2001,Cyclophosphamide,Fludarabine
地点
Canada
申办方
University Health Network, Toronto
正在招募 Phase 2 药物
clinicaltrials.gov NCT07372352

Zeprumetostat, Azacitidine Combined With Lipo-MIT in R/R PTCL

适用疾病
Peripheral T Cells Lymphoma (PTCL)
干预
Zeprumetostat,Azacitidine (AZA),Mitoxantrone Hydrochloride Liposome
地点
China
申办方
The First Affiliated Hospital of Soochow University
正在招募 Phase 1, Phase 2 药物手术/操作
clinicaltrials.gov NCT04315324

Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

适用疾病
Recurrent T Acute Lymphoblastic Leukemia;Refractory T Acute Lymphoblastic Leukemia;Refractory T Lymphoblastic Lymphoma
干预
AKR1C3-activated Prodrug AST-3424,Biopsy Procedure,Biospecimen Collection,Bone Marrow Aspiration
地点
United States
申办方
SWOG Cancer Research Network
正在招募 阶段未标明 药物手术/操作放疗
clinicaltrials.gov NCT07074470

Combination Regimen of Teniposide, PD-1 Monoclonal Antibody and Selinixor for Patients With Relapsed or Refractory PCNSL

适用疾病
Primary Central Nervous System Lymphoma (PCNSL)
干预
Induction therapy-2 cycles of VPX (Teniposide, PD-1 monoclonal antibody plus Selinixor),Consolidation therapy with ASCT after TB (Thiotepa plus Busulfan) preconditioning,Consolidation therapy-4 cycles of VPX (Teniposide, PD-1 monoclonal antibody plus Selinixor),Consolidation therapy-whole brain radiation therapy
地点
China
申办方
The First Affiliated Hospital of Soochow University
即将招募 Phase 1, Phase 2 器械药物
clinicaltrials.gov NCT07175415

HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

适用疾病
Acute Lymphoblastic Leukemia;Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent;Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
干预
Capivasertib,Venetoclax,Dexamethasone,Intrathecal chemotherapy
地点
未列出
申办方
Princess Maxima Center for Pediatric Oncology
正在招募 Phase 1 药物
clinicaltrials.gov NCT07350863

U69-CART-Cells For R/R T-ALL

适用疾病
Relapsed/Refractory T-lymphoblastic Leukemia/Lymphoma
干预
CXCR4 CCR9 CAR-T
地点
China
申办方
The First Affiliated Hospital of Soochow University
正在招募 Phase 2 药物
clinicaltrials.gov NCT06712121

Venetoclax and Decitabine in R/R T-ALL

适用疾病
T Lymphoblastic Leukemia/Lymphoma
干预
decitabine plus venetoclax
地点
South Korea
申办方
Seoul National University Hospital
正在招募 Phase 3 生物制剂药物
clinicaltrials.gov NCT05947851

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

适用疾病
Leukemia, Lymphocytic, Chronic, B-Cell;Leukemia, Chronic Lymphocytic;Small-Cell Lymphoma
干预
Nemtabrutinib,Venetoclax,Rituximab
地点
United States,Argentina,Australia,Belgium 等 14 个
申办方
Merck Sharp & Dohme LLC
正在招募 Phase 1, Phase 2 药物
clinicaltrials.gov NCT07070219

A Study of CTD402 in T-ALL/LBL Patients

适用疾病
Acute Lymphocytic Leukemia Refractory;Lymphoma, Lymphoblastic
干预
CTD402 CAR T Cell Injection
地点
United States
申办方
BIOHENG THERAPEUTICS US LLC
即将招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT07678307

A Multicenter, Open-label, Non-randomized, Single-arm Phase 1/2 Study of Autologous Nano CD5-CAR T Cells for the Treatment of Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia/Lymphoma

适用疾病
T-Cell Acute Lymphoblastic Leukemia;T-Lymphoblastic Lymphoma;Relapsed/Refractory Hematologic Malignancies
干预
Autologous nano CD5-CAR T Cells
地点
未列出
申办方
Institute of Hematology & Blood Diseases Hospital, China
正在招募 EARLY / Phase 1 生物制剂药物
clinicaltrials.gov NCT06756321

A Study of CAR T-Cells in Relapsed/Refractory Hematologic Malignancy

适用疾病
Relapsed/refractory Lymphoma;Relapsed/Refractory Leukemia
干预
anti-CD19-CAR T-cells, or anti-CD30-CAR T-cells, or anti-CD20/CD30-CAR T-cells,Fludarabine,Cyclophosphamide
地点
China
申办方
Affiliated Hospital of Nantong University
正在招募 Phase 1, Phase 2 生物制剂药物
clinicaltrials.gov NCT06364423

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias

适用疾病
Leukemia, Lymphocytic, Chronic, B-Cell;B-Lymphocytic Leukemia, Chronic;B-Cell Chronic Lymphocytic Leukemia
干预
Autologous HuCD19 ( Anti-CD19)CAR T cells,Cyclophosphamide,Fludarabine,Rituximab
地点
United States
申办方
National Cancer Institute (NCI)
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT07300683

Anti-CCR9 CAR T Cells for T Cell Leukaemia/Lymphoma

适用疾病
T Cell Acute Lymphoblastic Leukemia;T Cell Lymphoblastic Lymphoma
干预
CARCCR9 T cells
地点
United Kingdom
申办方
University College, London
即将招募 Phase 1 生物制剂
clinicaltrials.gov NCT07297160

CD70.CAR for CD70+ Lymphoma, Myeloma and Solid Tumors

适用疾病
Lymphoma;Myeloma;Solid Tumors
干预
Dose Level -1,Dose Level 1 (starting dose level),Dose Level 2,Dose Level 3
地点
United States
申办方
Baylor College of Medicine
正在招募 Phase 1, Phase 2 生物制剂
clinicaltrials.gov NCT04033302

Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies

适用疾病
T-cell Acute Lymphoblastic Leukemia;T-cell Acute Lymphoblastic Lymphoma;Acute Myeloid Leukemia
干预
CD7-specific CAR gene-engineered T cells
地点
China
申办方
Shenzhen Geno-Immune Medical Institute
正在招募 Phase 1 生物制剂
clinicaltrials.gov NCT05995028

Universal 4SCAR7U Targeting CD7-positive Malignancies

适用疾病
T-cell Acute Lymphoblastic Leukemia;T-cell Acute Lymphoblastic Lymphoma;Acute Myeloid Leukemia
干预
Universal CD7-specific CAR gene-engineered T cells
地点
China
申办方
Shenzhen Geno-Immune Medical Institute
正在招募 阶段未标明 生物制剂
clinicaltrials.gov NCT05620680

CD7 CAR-T Cells in T-cell Lymphoma/Leukemia

适用疾病
T Lymphoblastic Leukemia/Lymphoma
干预
CD7 CAR-T cells
地点
China
申办方
Shenzhen University General Hospital
第 1 页

Subtypes

建议拆分方向

DLBCLfollicular lymphomaHodgkin lymphomamantle cell lymphomarelapsed refractory lymphomaCAR-Tbispecific antibodyCD19CD20

Keywords

英文搜索关键词

Keyword guide

这些关键词怎么理解

术语中文意思对找临床试验有什么用
DLBCL 弥漫大 B 细胞淋巴瘤,是常见非霍奇金淋巴瘤类型。 很多 CAR-T、双抗和新药试验会专门招 DLBCL。
滤泡性淋巴瘤 / Follicular lymphoma 一种常见惰性 B 细胞淋巴瘤。 搜索时要和 DLBCL 分开,试验条件不同。
霍奇金淋巴瘤 / Hodgkin lymphoma 与非霍奇金淋巴瘤不同的一大类淋巴瘤。 可以找 PD-1、CD30、复发难治相关试验。
Relapsed / refractory 复发或难治,指治疗后复发或对治疗反应不理想。 很多海外血液肿瘤试验会限定 R/R 患者。
CAR-T 一种细胞治疗方式,常见靶点包括 CD19 等。 可以找 CAR-T、cell therapy、CD19 相关试验。
Bispecific antibody 双特异性抗体,常见方向包括 CD20xCD3 等。 复发难治淋巴瘤中常见研究方向。

Recruitment status

常见招募状态

Recruiting正在招募,可能仍可申请参加。
Not yet recruiting尚未开始招募,可关注后续开放时间。
Active, not recruiting试验仍在进行,但通常不再招新患者。
Completed试验已经完成。
Terminated试验提前终止。
Unknown公开页面上的状态不明确或未及时更新。

Before contact

联系前准备资料

  • 病理诊断报告
  • 影像报告:CT / MRI / PET-CT
  • 既往治疗记录
  • 用药历史
  • 基因检测报告
  • 最近血液检查结果
  • 出院小结
  • 主治医生英文病情摘要,如果有
  • 护照和签证情况,如果考虑出国

Filters

搜索时重点关注

  • Recruiting / Not yet recruiting
  • Location
  • Age
  • Phase
  • Inclusion Criteria
  • Exclusion Criteria
  • Prior treatments
  • Biomarker / mutation requirements
  • ECOG performance status
  • 是否接受 international patients
  • 是否需要长期停留在试验所在地
  • 费用、保险、翻译、住宿和陪护安排

Ask your doctor

可以带去问医生的问题

  • 我的病理类型是否符合这个试验?
  • 我之前用过的药会不会影响入组?
  • 我是否需要做基因检测?
  • 这个试验是几期?主要目的是什么?
  • 参加试验会不会影响当前治疗?
  • 如果去国外参加,风险和成本大概有哪些?
  • 研究团队是否接受海外患者?
下一步提示

请将检索到的临床试验信息带给主治医生或肿瘤科医生讨论。本站不判断患者是否适合任何临床试验。